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This study presents an innovative breast reconstruction technique using an axillary single-port endoscopic approach with immediate breast reconstruction for breast cancer. The procedure begins with a concealed incision along the axillary fold that serves as a sentinel lymph node biopsy and endoscopic access. Under high-definition endoscopic visualization, meticulous dissection of the posterior space of the pectoralis major muscle and the retromammary space is performed, preserving critical neurovascular structures. A unique subcutaneous tunneling technique using long curved scissors enables the thorough separation of the breast parenchyma from the subcutaneous tissues, facilitating the en bloc resection of the mammary glands. The nipple-areolar complex was subjected to intraoperative frozen section analysis to confirm margin clearance. A critical step involves expertly folding and turning the patch upward before inserting it along the free edge of the pectoralis major muscle, where it is secured in place through continuous suturing. Surgical innovation is centered on patch manipulation protocols. The prosthesis is meticulously wrapped in a downwardly positioned patch to ensure complete enclosure and protection. The findings of this study strongly suggest that this single-port axillary endoscopic radical mastectomy, complemented by an innovative downward patch-wrapping technique, represents an effective and superior approach for the treatment of breast cancer, providing favorable outcomes and improved recovery experiences. This procedure was successfully performed in 30 patients at our hospital, with an average operating time of 147.73 min and a mean follow-up period of 17 months, and the BREAST-Q score post-operation was higher than that of pre-operation. These results indicate significant advantages over traditional reconstruction methods regarding aesthetic outcomes and postoperative recovery.
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http://dx.doi.org/10.3791/68215 | DOI Listing |
J Surg Case Rep
September 2025
Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, 200 Medical Plaza, Suite 460, Los Angeles, CA 90095, United States.
Tuberous breast deformity was first documented by Rees and Aston in 1976. The deformity is well documented in cisgender women, with rare cases in cisgender men often associated with gynecomastia, and almost no reports in transgender women. Herein, we present a case of a 32-year-old transgender woman who developed bilateral tuberous breast deformity after 10 years of hormone replacement therapy.
View Article and Find Full Text PDFCureus
August 2025
Medicine, Academy of Silesia, Katowice, POL.
We present the case of a 45-year-old Caucasian woman diagnosed with synchronous bicentric breast cancer of differing molecular phenotypes in the same breast. The first tumor, an invasive ductal carcinoma (G1), was estrogen and progesterone receptor-positive and HER2-negative, with a low proliferative index (Ki67 10%). A second lesion, located in a different quadrant and appearing within weeks after biopsy, exhibited a triple-negative phenotype and a higher proliferative index (Ki67 30%).
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Medical and Pharmaceutical Affairs, Doctor CONSULT, Seoul, Korea.
Stakeholders in the breast implant industry in Korea have recently experienced a crisis from breast implant-associated anaplastic large cell lymphoma and the first Korean case of a medical device fraud. We compared the short-term safety between the microtextured devices that are commercially available after the occurrence of breast implant crisis in Korea. The current study was conducted in a cohort of Korean women who had received an implant-based augmentation mammaplasty for aesthetic purposes between November 14, 2020 and October 13, 2022.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Department of Chemical and Biological Engineering, Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science & Technology, Hong Kong, 999077,
Breast cancer (BC), characterized by its heterogeneity and diverse subtypes, necessitates personalized treatment strategies. This study presents MF3Ec-TBPP nanoparticles (NPs) as a promising approach, integrating an aggregation-induced emission (AIE)-based photosensitizer, TBPP, with the MF3Ec aptamer to enhance targeted photodynamic therapy (PDT) for Luminal A subtype BC cells. The nanoparticles also feature a 1, 2-distearoyl-sn-glycero-3-phosphoethanolamine-poly(ethylene glycol) shell and dipalmitoyl phosphatidylcholine (DPPC), which stabilize the structure and inhibit singlet oxygen generation, effectively reducing off-target effects and protecting healthy tissues.
View Article and Find Full Text PDFAesthet Surg J
September 2025
Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Background: Patient electronic communication (PEC) via secure messaging is important for patient engagement. While PEC has been studied in primary care, data on surgical specialties, particularly plastic surgery, remain limited.
Objectives: This study assessed the volume and content of post-discharge PECs among patients undergoing post-mastectomy autologous breast reconstruction.