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Article Abstract
Purpose: Conventional intracavitary brachytherapy (ICBT) operative procedures with tandem-ring (TR) applicators utilizing standard rectal retractor (RR) blades for rectum separation did not allow for optimal rectum sparing, especially in patients with roomy vagina. This limitation was overcome by modifying the technique by placing customized vaginal packing (VP) alongside a standard RR blade based on the patient specific spacial constraints to supplement the rectum displacement. The paper compares the modified technique with the conventional technique of using RR alone on the International Commission on Radiation Units and Measurements-38 (ICRU-38) rectum and bladder point doses.
Methods: Between January 2021 and August 2022, 41 cancer patients received at least one ICBT fraction with the conventional and at least one with the modified technique for rectum separation using the same applicator set and loading pattern. The remaining ICBT fractions were done using that technique, which gave the best dosimetric parameters during previous fractions in that particular patient.
Results: Out of the 111 ICBT fractions utilizing TR applicators, 44 fractions done with the conventional technique constitute conventional group, whereas 67 fractions with the modified technique constitute the modified group. For the same dose (100%) prescribed to point A in both groups, the mean dose to the ICRU rectal point was 44.1% of the prescription dose (range: 23.8-77.8%, median: 42.5%) in modified group and 55.5% (range: 36.4-73.1%, median: 56.5%) in the conventional group. There was 11.4% reduction in mean dose to the ICRU rectal point (p < 0.001) in the modified group. The other point doses and volume parameters were similar between the two groups.
Conclusion: Modified technique of combining rectal retractor with customised vaginal packing significantly reduced the ICRU rectal point dose, compared to using a rectal retractor alone during brachytherapy with tandem-ring applicators.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12182075 | PMC |
| http://dx.doi.org/10.2147/CMAR.S520276 | DOI Listing |
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