98%
921
2 minutes
20
Background: The p factor represents the overall liability for the development of mental illness within individuals and we have previously validated a bi-factor model of the p factor in children with chronic physical illness.
Objective: In this next phase, we modelled predictors of the p factor in this sample of children.
Methods: Data come from the ongoing Multimorbidity in Children and Youth Across the Life-course study. Data from 263 children with a chronic physical illness aged 2-16 years and their parents were collected over 24 months. The parent-reported Emotional Behavioural Scales was used to develop a bi-factor model of the p factor. Subsequently, p factor scores were extracted from the model and standardized (Mean = 100, SD = 15). Analysis of variance compared p factor scores across different physical illnesses. Multiple regression was used to identify multilevel baseline predictors of p scores.
Results: There was no significant difference in p scores across categories of physical illness (F = 0.44, p = 0.849). Factors predictive of elevated p scores were older child age (B = 0.44), higher level of disability (B = 1.03), elevated parent psychopathology (B = 0.22) and stress (B = 0.21), and living in communities with older age and lower labor force participation (B = 1.66) and higher concentrations of racialized/newcomer populations (B = 2.05). Lower p scores were associated with being female (B = -3.85) and having immigrant parents (B = -5.43).
Conclusion: Factors predicting psychopathology, measured using p scores, in children with physical illness are multilevel. Fixed characteristics can inform targeted screening efforts, whereas modifiable characteristics are opportunities for upstream intervention in the context of family-centered integrated physical-mental health services.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jpsychires.2025.06.023 | DOI Listing |
Trends Psychiatry Psychother
September 2025
Laboratory of Hormone Measurement, Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Brazil. Postgraduate Program in Psychobiology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil. National Institute of Science and Technology fo
Background: Major Depressive Disorder (MDD) is a leading cause of global disability, contributing to substantial individual, social, and economic burdens. While antidepressant therapy remains the cornerstone of treatment, complementary lifestyle-based interventions, such as multimodal exercise and mindfulness, have shown promise in alleviating mood symptoms. However, their specific impact on sleep quality, a critical therapeutic target in MDD, remains underexplored.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Critical Illness, Brain Dysfunction, and Survivorship Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Importance: Survivors of critical illness often have ongoing issues that affect functioning, including driving ability.
Objective: To examine whether intensive care unit (ICU) delirium is independently associated with long-term changes in driving behaviors.
Design, Setting, And Participants: This multicenter, longitudinal cohort study included 151 survivors of critical illness residing within 200 miles of Nashville, Tennessee.
Community Ment Health J
September 2025
The University of Queensland, Herston, Australia.
Engaging residents with the support available at community-based residential mental health rehabilitation facilities is an ongoing challenge for health services. This study explored factors associated with residential rehabilitation engagement across Queensland, Australia through regression modelling of cross-sectional data from a statewide benchmarking activity completed in 2023 (n = 208). The Residential Rehabilitation Engagement Scale (RRES) assessed each resident's rehabilitation engagement.
View Article and Find Full Text PDFInfect Dis Ther
September 2025
Department of Nursing, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, China.
Introduction: Cognitive frailty (CF), which typically precedes dementia and functional decline, serves as a more robust predictor of adverse health outcomes compared to physical frailty alone, representing a critical challenge in promoting healthy aging among older people living with HIV (PLWH) aged ≥ 50 years. This study aimed to investigate the prevalence of cognitive frailty and identify its associated factors among PLWH aged ≥ 50 years.
Methods: A convenience sample of 344 PLWH ≥ 50 years was recruited from a tertiary Grade A hospital in Zunyi, China.
Metab Brain Dis
September 2025
Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277, Jiefang Avenue, Wuhan, Hubei, 430022, China.
Major depression disorder (MDD) is a mental condition that significantly threatens both physical and psychological health. This study aimed to discern variances in plasma metabolic profiles between MDD sufferers and healthy counterparts. Additionally, we tracked the hospitalization journey of MDD patients to investigate the normalization of metabolic irregularities through conventional treatment in the form of self-control.
View Article and Find Full Text PDF