98%
921
2 minutes
20
Objective: Automated air-conduction pure-tone audiograms through Bayesian estimation and machine learning (ML) classification have recently been proposed in the literature. Although such ML-based audiometry approaches represent a significant addition to the field, they remain unsuited for daily clinical settings, in particular for listeners with asymmetric or conductive hearing loss, severe hearing loss, or cochlear dead zones. The goal here is to expand on previously proposed ML approaches and assess the performance of this improved ML audiometry for a large sample of listeners with a wide range of hearing status.
Methods: First, we describe the changes made to the ML method through the addition of: (1) safety limits to test listeners with a wide range of hearing status, (2) transient responses to cater for cochlear dead zones or nonmeasurable thresholds, and importantly, (3) automated contralateral masking to test listeners with asymmetric or conductive hearing loss. Next, we compared the performance of this improved ML audiometry with conventional and manual audiometry in a large cohort ( = 109 subjects) of both normal-hearing and hearing-impaired listeners.
Results: Our results showed that for all audiometric frequencies tested, no significant difference was found between hearing thresholds obtained using manual audiometry on a clinical audiometer as compared to both the manual and automated improved ML methods. Furthermore, the test-retest difference was not significant with the automated improved ML method for each audiometric frequency tested. Finally, when examining cross-clinic reliability measures, significant differences were found for most audiometric frequencies tested.
Conclusions: Together, our results validate the use of this improved ML-based method in adult clinical tests for air-conduction audiometry.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12172120 | PMC |
http://dx.doi.org/10.1002/wjo2.208 | DOI Listing |
Cereb Cortex
August 2025
Department of Psychology, University of Lübeck, Ratzeburger Allee 160, Lübeck 23562, Germany.
The human auditory system must distinguish relevant sounds from noise. Severe hearing loss can be treated with cochlear implants (CIs), but how the brain adapts to electrical hearing remains unclear. This study examined adaptation to unilateral CI use in the first and seventh months after CI activation using speech comprehension measures and electroencephalography recordings, both during passive listening and an active spatial listening task.
View Article and Find Full Text PDFMol Biol Rep
September 2025
Cytogenetics and Molecular Genetics Lab, Pathology Unit, Medical Division (BARC Hospital), Bhabha Atomic Research Centre, Anushakti Nagar, Mumbai, India.
Background: Hearing loss (HL) is one of the most common congenital anomalies and is a complex etiologically diverse condition. Molecular genetic characterization of HL remains challenging owing to the high genetic heterogeneity. This study aimed to screen for potential disease-causing genetic variations in a cohort of Indian patients with congenital bilateral severe-to-profound sensorineural HL.
View Article and Find Full Text PDFBrain Behav
September 2025
Radiology Department, Yantaishan Hospital, Yantai, Shandong, China.
Objective: To investigate the characteristics of brain structures in patients with noise-induced hearing loss (NIHL) using source-based morphometry (SBM) and to evaluate the correlation between abnormal brain regions and clinical data.
Methods: High-resolution 3D T1 structural images were acquired from 81 patients with NIHL and 74 age- and education level-matched healthy controls (HCs). The clinical data of all subjects were collected, including noise exposure time, monaural hearing threshold weighted values (MTWVs), Mini-Mental State Examination (MMSE), and Hamilton Anxiety Scale (HAMA) scores.
Phys Ther
September 2025
Dirección de Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Importance: To this author's knowledge, this is the first study to examine the burden of rehabilitation-relevant conditions in Mexico, providing valuable evidence to inform public policy and enhance the delivery of rehabilitation services.
Objective: This study presents a national-level analysis estimating the number of people in Mexico who required rehabilitation at least once during the course of an illness or injury that caused a disability, based on data from the 2021 Global Burden of Disease Study.
Design: This was a cross-sectional analysis.
MedComm (2020)
September 2025
modulates presynaptic Ca1.3 Ca channel function in inner hair cells (IHCs) and is required for indefatigable synaptic sound encoding. Biallelic variants in are associated with non-syndromic hearing loss (DFNB93).
View Article and Find Full Text PDF