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Despite nationally reported metrics that suggest high levels of water security, approximately 12% of the United States of America (US) population is estimated to be water insecure based on the definition in United Nations (UN) SDG 6.1.1. Approximately half of these households are served by Decentralized Water Systems (DWS). In contrast, most research, engineering, innovation, and government programs are focused on Centralized Water Systems (CWS). In this perspective, we 1) characterize and define DWS using professional language common for CWS; 2) compare the social, economic, and regulatory responsibilities of stakeholders in each system; 3) outline existing strategies to professionalize this sector; and 4) propose research avenues to further professionalize DWS to ensure households served by these systems receive equitable water service. We demonstrate that while DWS share commonalities with CWS, decentralized systems are less formally structured; have more stakeholders between source and tap; and place much of the regulatory, finance, maintenance, and safety responsibilities on individual households. These responsibilities include ensuring water quantity and quality, selecting appropriate treatment technologies, finance of repairs and upgrades, and transporting water. We propose strategies for researchers to aid in codeveloping innovative DWS solutions, ensuring relevant integration and community-driven models that better support decentralized communities.
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http://dx.doi.org/10.1021/acsestwater.5c00064 | DOI Listing |
J Sep Sci
September 2025
Programa De Pós-Graduação em Química, Universidade Federal de Sergipe, São Cristóvão, Sergipe, Brazil.
Secondary metabolites are important bioactive compounds for diet and medicine. This study optimizes the extraction of hydroethanolic herbal extracts using an EDGE (Energized Dispersive Guided Extraction) system, evaluates their antioxidant capacity, and analyzes correlations among antioxidant activity, total phenolic content, and individual compounds. A Doehlert matrix design was used to optimize extraction, having temperature and time as independent variables, and total phenolic content (mg GAE/g) as the response, quantified via the Folin-Ciocalteu method.
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Fisheries Research Institute, Sichuan Academy of Agricultural Sciences, Chengdu, 611730, China.
Background: Fish are the largest group of vertebrates. Studying the characteristics, functions, and interactions of different fish cells is important for understanding their roles in disease and evolution. However, most single cell RNA-seq studies in fish are restricted to a few specific organs, leaving a comprehensive cell landscape that aims to characterize the heterogeneity and connections among body-wide organs largely unexplored.
View Article and Find Full Text PDFFundam Clin Pharmacol
October 2025
Postgraduate Program in Pharmaceutical Science, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
This review highlights the integration of drug repurposing and nanotechnology-driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidiasis, providing a framework for future translational research and clinical application. The rising prevalence of antifungal resistance and virulence factors of Candida albicans underscore the limitations of current therapies. Statins, commonly used as lipid-lowering agents, have emerged as attractive repurposed drug candidates due to their ability to interfere with fungal ergosterol biosynthesis and Ras-mediated signaling pathways.
View Article and Find Full Text PDFAmbio
September 2025
Department of Sustainable Development, Environmental Science and Engineering (SEED), KTH Royal Institute of Technology, Stockholm, Sweden.
This study investigates how the seven core resilience principles are integrated into assessments of forest system resilience to natural or human-induced disturbances across engineering, ecological, and social-ecological resilience concepts. Following PRISMA guidelines, a literature search in the Web of Science database using the keywords "resilience", "forest" and "ecosystem services" yielded 1828 studies, of which 330 met the selection criteria. The most commonly used criterion was diversity, a sub-criterion of "diversity and redundancy", appearing in 50% of studies.
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September 2025
Marine and Continental Waters, IRTA, Ctra. Poble Nou km 5.5, 43540, La Ràpita, Spain.
Palytoxin-like compounds, including ovatoxins, are potent emerging toxins responsible for human respiratory poisonings following inhalation of contaminated marine aerosols. Periodic massive proliferations of the ovatoxin-producing organism (Ostreopsis cf. ovata) worldwide, particularly in the Mediterranean, have caused severe toxic outbreaks, drawing the attention of health authorities.
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