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| http://dx.doi.org/10.1016/j.jri.2025.104617 | DOI Listing |
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[Morpho-functional features of the endometrium in uterine leiomyoma before and after embolization of the uterine arteries].
Arkh Patol
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G.M. Savelyeva City Clinical Hospital No. 31, Moscow, Russia.
Unlabelled: The question of the degree of influence of uterine artery embolization (UAE) on fertility is open. It is important to evaluate the pathomorphological structure and functional activity of the endometrium, the disruption of which can lead to infertility.
Objective: To study morpho-functional changes in the endometrium of patients with uterine fibroids before and after UAE.
Endometrial microbiome during early pregnancy among women with and without chronic endometritis: a pilot study.
Front Cell Infect Microbiol
August 2025
Ottawa Hospital Research Institute, the Ottawa Hospital, Ottawa, ON, Canada.
Introduction: Although chronic endometritis (CE) is strongly associated with infertility and adverse pregnancy outcomes, the specific microbiome of women with CE who can conceive remain unclear.
Methods: This study recruited 100 participants aged 18 to 45 years with spontaneously conceived pregnancy who opted for pregnancy termination, detected their endometrial microbiome by 16S rRNA, and made a diagnosis of CE.
Results: Among them, 19 were diagnosed with CE.
Endometriosis, chronic endometritis (CE), unexplained infertility (UI), and recurrent pregnancy loss (RPL) are gynecological conditions frequently associated with inflammation and alterations in the endometrial microbiome. The presence of bacterial vaginosis-associated bacteria (BVAB) and the expression of CD138 may influence clinical outcomes. We evaluate the relationship between endometrial BVAB detection via qPCR, CD138 marker expression, prior antibiotic treatment, and the number of miscarriages.
View Article and Find Full Text PDFClinicopathological Insights Into Endometrial Osseous Metaplasia: A Rare Case Report.
Case Rep Pathol
August 2025
Department of Pathology, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
Endometrial osseous metaplasia is a rare entity encountered in the reproductive age group characterized by the presence of mature bone within the endometrium. Most of the cases are associated with secondary infertility, with a past history of abortion or chronic endometritis. Various hypotheses, such as chronic inflammation, dystrophic calcification, and residual embryonic tissue, have been proposed for the etiopathogenesis.
View Article and Find Full Text PDFThe effect of autologous platelet-rich plasma intrauterine perfusion on pregnancy outcomes of frozen-thawed embryo transfer in patients with chronic endometritis.
Front Reprod Health
August 2025
Department of Cardiology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Objective: To analyze the effect of autologous platelet-rich plasma (PRP) intrauterine perfusion on the clinical outcomes of frozen-thawed embryo transfer in patients with chronic endometritis.
Methods: A retrospective continuous cohort of 219 patients diagnosed with chronic endometritis at the Reproductive Medicine Center of Affiliated Hospital of Putian University between January 2020 and December 2022, undergoing their first frozen-thawed embryo transfer cycle, was included. All patients received standardized oral doxycycline treatment after diagnosis.