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Using soft wearable electronics has emerged as an innovative neurological disorder monitoring and rehabilitation approach. Traditional diagnostic and treatment systems are hospital-centered, bulky, and unsuitable for long-term use, limiting their applicability in real-world settings. Recent advancements in materials, device design, and fabrication processes have enabled the development of stretchable, skin-conformal sensors, improving wearability, signal quality, and usability. This review discusses key design considerations for ensuring conformal integration with the human body, covering aspects from materials selection to structural engineering. Additionally, we explore recent research trends in soft electronics-based electrophysiological and physical activity sensors and the system integration challenges that must be addressed for clinical applications. Finally, we introduce emerging neurological disorder applications utilizing soft wearable electronics, highlighting their limitations and potential. By addressing these challenges, soft wearable electronics will advance continuous health monitoring, personalized rehabilitation, and next-generation neuroprosthetic systems.
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http://dx.doi.org/10.1039/d5mh00528k | DOI Listing |
Mater Horiz
September 2025
TU Delft, Netherlands.
Soft wearable sensors offer promising potential for advanced diagnostics, therapeutics, and human-machine interfaces. Unlike conventional devices that are bulky and rigid, often compromising skin integrity, comfort, and user compliance, soft wearable sensors are flexible, conformable, and better suited to the dynamic skin surface. This improved mechanical integration enhances signal fidelity and device performance, while also enabling safer, more comfortable, and continuous physiological monitoring in real-world environments.
View Article and Find Full Text PDFAdv Colloid Interface Sci
September 2025
Key Laboratory of Colloid and Interface Chemistry (Ministry of Education), Shandong University, Jinan 250100, PR China. Electronic address:
Multiple stretchable gels with conductivity have been thoroughly prepared in diverse solvents historically to modulate their superlative properties in a multitude of applications, such as soft robotics, wearable devices, and e-skins. Eutectogels are considered as an emerging class of gels that combine the best features of both hydrogels and organogels, including environmental friendliness, thermal stability and customizable nature. Eutectogels, composed of deep eutectic solvents (DES) immobilized within different matrices, not only inherit the merits of DES, but also show some additional properties derived from the special structure and compositions, which are conducive to development potential.
View Article and Find Full Text PDFSci Adv
September 2025
School of Biomedical Engineering, ShanghaiTech University, Shanghai, China.
Developing intelligent robots with integrated sensing capabilities is critical for advanced manufacturing, medical robots, and embodied intelligence. Existing robotic sensing technologies are limited to recording of acceleration, driving torque, pressure feedback, and so on. Expanding and integrating with the multimodal sensors to mimic and even surpass the human feeling is substantially underdeveloped.
View Article and Find Full Text PDFAdv Mater
September 2025
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, P. R. China.
Liquid crystal elastomers (LCEs) are important soft actuators that show strong promise in many fields where traditional rigid actuators or robotics are impractical. However, their real-world applications are lacking primarily due to inadequate actuation performance and complicated fabrication processes. Here, a novel design is reported that significantly enhances actuation performance while simplifying the fabrication process.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Department of Mechanical Engineering, State University of New York at Binghamton, Binghamton, New York 13902, United States.
Soft conductive composites are significant components of soft and wearable electronics. Existing soft conductive composites encounter difficulties in attaining 10% of copper's electrical conductivity while maintaining high stretchability. In this work, a novel "soft conductive junction" concept is introduced to overcome the conductivity-stretchability trade-off.
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