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Objectives: To explore the impact of virtual reality (VR) intervention on motor function (MF) and activities of daily living (ADL) in children and adolescents with cerebral palsy (CP), and to identify effective VR intervention strategies.
Data Sources: Searches were conducted in PubMed, Wiley Online Library, Embase, Cochrane Library, and Web of Science (all collections).
Study Selection: All randomized controlled trials (RCTs) of VR intervention on MF and ADL in children and adolescents with CP.
Data Extraction: We conducted dual data abstraction, quality assessment, and strength of evidence. Outcomes include gait, balance, gross MF (GMF), ADL, and hand function.
Data Synthesis: This review encompassed 41 RCTs focusing on the use of VR intervention for children and adolescents with CP. The effect of VR intervention on gait (standardized mean difference [SMD]=0.52; 95% confidence interval [CI], 0.18-0.85) and GMF (SMD=0.76; 95% CI: 0.17, 1.34) has a moderate effect, while balance (SMD=1.1; 95% CI, 0.61-1.59), ADL (SMD=1.46; 95% CI, 0.71-2.2), and hand function (SMD=1.08; 95% CI, 0.17-2) have a great effect. Subgroup analysis reveals the influence of different intervention parameters on different functions. For example, balance is related to the intervention duration of >10 weeks, the frequency of 1-2 times per week, the Nintendo Wii platform, and nonimmersive VR.
Conclusion: Although the results show that VR intervention has a positive impact on MF and ADL, the high heterogeneity limits the stability of the conclusion. Future research needs to further explore the mechanism of VR intervention and try to set a reliable personalized intervention model.
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http://dx.doi.org/10.1016/j.apmr.2025.06.001 | DOI Listing |
JMIR Public Health Surveill
September 2025
Department of Preventive Medicine, College of Medicine, Korea University, 73 Goryeodae-ro, Seoungbuk-gu, Seoul, 02841, Republic of Korea, 82 2-2286-1169.
Background: Scrub typhus (ST), also known as tsutsugamushi disease, is a common febrile vector-borne illness in South Korea, transmitted by trombiculid mites infected with Orientia tsutsugamushi, with rodents serving as the main hosts. Although vector-borne diseases like ST require both a One Health approach and a spatiotemporal perspective to fully understand their complex dynamics, previous studies have often lacked integrated analyses that simultaneously address disease dynamics, vectors, and environmental shifts.
Objective: We aimed to explore spatiotemporal trends, high-risk areas, and risk factors of ST by simultaneously incorporating host and environmental information.
J Sex Marital Ther
September 2025
Department of Psychiatry, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
The etiology of gender dysphoria (GD) involves both biological and psychosocial factors and may have a neurodevelopmental aspect. We aimed to compare individuals with GD with each other and with cisgender individuals based on minor physical anomalies (MPAs). The case group comprised 108 individuals with GD (60 GD assigned female at birth [AFAB]; 48 GD assigned male at birth [AMAB]), most with same-biological-sex attraction.
View Article and Find Full Text PDFEpidemiol Serv Saude
September 2025
Universidade Federal do Rio Grande do Sul, Programa de Pós-Graduação em Saúde Coletiva Porto Alegre, RS, Brazil.
Objective: To analyze the mental health of Brazilian adolescent mothers who use the Unified Health System (Sistema Único de Saúde, SUS).
Methods: This is a multicenter study conducted with 583 adolescent mothers (10-19 years old). The participants responded to a questionnaire on sociodemographic variables, mental health and family support.
J Bras Pneumol
September 2025
. Programa de Pós-Graduação em Ciências Médicas, Universidade Federal de Santa Catarina, Florianópolis (SC) Brasil.
Objective: To describe the impact of severe asthma in a real-life cohort in Brazil, reporting on baseline clinical characteristics, access to treatment, and clinical remission under treatment with biologics.
Methods: Severe asthma patients > 6 years of age were recruited from 23 centers in Brazil. Data on clinical characteristics, lung function, biomarkers, prescribed therapies, and clinical remission under treatment were collected at the baseline visit.
Arq Gastroenterol
September 2025
Escola Superior de Ciências da Saúde, Fundação de Ensino e Pesquisa em Ciências da Saúde, Brasília, DF, Brasil.
Objectives: This study aimed to translate the Neurogenic Bowel Dysfunction Score into Brazilian Portuguese, adapting it culturally and validating it semantically.
Methods: The process followed international guidelines for translation, back-translation, cultural adaptation, and semantic validation, involving a committee of specialists and a pre-test with 10 Brazilian pediatric patients with neurogenic bowel dysfunction (mean age: 11 years). Participants were divided into two groups, depending on whether they used transanal irrigation for intestinal management.