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Article Abstract

Background And Aims: The use of fractional flow reserve (FFR) and resting full-cycle ratio (RFR) for assessing intermediate coronary lesions is well-established. However, discordance between these methods occurs in 15%-25% of cases. The objective is to identify clinical and angiographic predictors of discordance between FFR and RFR in a Spanish cohort.

Methods: A prospective cohort study of 94 patients with 107 intermediate coronary lesions was conducted. FFR and RFR were measured, and logistic regression was used to identify predictors of discordance.

Results: Discordance occurred in 15.9% of cases. Independent predictors were active smoking, lesions in the left anterior descending artery, and higher area stenosis percentage.

Conclusion: Smoking, LAD lesions, and stenosis severity predict discordance between FFR and RFR. Further studies are needed to clarify the phenomena that cause such discordance.

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http://dx.doi.org/10.1002/ccd.31682DOI Listing

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