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Predicting epileptic seizures presents a substantial difficulty in healthcare, with considerable implications for enhancing patient outcomes and quality of life. This paper presents an explainable artificial intelligence (AI) that integrates a one-dimensional convolutional neural network (1D-CNN) with SHapley Additive exPlanations (SHAP). The approach facilitates precise and interpretable seizure prediction utilising electroencephalography (EEG) inputs. The suggested 1D-CNN model with SHAP attains superior performance, exhibiting an accuracy of 98.14% and an F1-score of 98.30% with feature-level explainability and high clinical insight using the CHB-MIT dataset. Through the computation and aggregation of SHAP values across time, we identified the most significant EEG channels, specifically "P7-O1" and "P3-O1", as essential for seizure detection. This transparency is crucial for building practitioners' trust and acceptance of the use of artificial intelligence-based solutions in the clinical domain. The technique can readily operate within portable EEG structures and hospital monitoring systems, triggering real-time alerts to patients. The outcome provides a timely intervention that could include anything from medication adjustments to responses in emergencies, preventing potential injury and improving safety. So, SHAP not only explains the model's predictions, but it also check and improve how much it relies on certain features, which makes it more reliable. Additionally, SHAP's interpretability aids physicians in understanding why the model arrived at its conclusions, increasing trust in the predictions and encouraging its extensive utilisation in diagnostic processes.
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http://dx.doi.org/10.1007/s10916-025-02211-1 | DOI Listing |
Paediatr Perinat Epidemiol
September 2025
Department of Epidemiology and Occupational Health, McGill University, Montréal, Quebec, Canada.
Background: Studies show that foetal and birthweight-for-gestational age centiles are poor predictors of serious neonatal morbidity and neonatal mortality (SNMM) in univariable models.
Objective: We assessed the predictive performance of multivariable SNMM models based on maternal/pregnancy characteristics, with and without birthweight centiles.
Methods: The study was based on all live births in the United States, 2019-2021, with data obtained from the period live birth-infant death files of the National Center for Health Statistics.
Cureus
August 2025
Medicine, Fatima Jinnah Medical University, Lahore, PAK.
This study aimed to investigate the surgical management of cerebral arteriovenous malformations (AVMs) by analyzing clinical outcomes and complications in 600 patients (100%) who underwent surgery. The mean age of the cohort was 36.7 years (SD = 12.
View Article and Find Full Text PDFNeurol Clin Pract
October 2025
Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Program in Trauma, University of Maryland, Baltimore, MD.
Background And Objectives: Guidelines for super-refractory status epilepticus (SRSE) evaluation, management, and prognostication are lacking. Characterization of practice patterns could identify trends and potential areas for future inquiry. We surveyed clinicians who manage SRSE to better understand practice approaches to SRSE evaluation, management, and prognostication.
View Article and Find Full Text PDFJ Feline Med Surg
September 2025
Department for Small Animals, Veterinary Faculty, Leipzig University, Leipzig, Germany.
ObjectivesThe objective of this study was to evaluate the occurrence of voltage-gated potassium channel (VGKC) antibodies and the pattern of MRI changes in cats with complex partial seizures with orofacial involvement (CPSOFI), as well as to investigate whether there are factors influencing survival that could be used as prognostic markers in those cats.MethodsCats with CPSOFI were identified retrospectively. The following data were retrieved from the hospital database: signalment, age at first seizure and presentation, the presence of antibodies against VGKC (leucine-rich glioma inactivating factor 1 (LGI1), contactin-associated protein 2 (CASPR2)) and cerebrospinal fluid (CSF) analysis findings.
View Article and Find Full Text PDFNeurochirurgie
September 2025
Department of neurosurgery, Toulouse University Hospital, place du Docteur Baylac, Toulouse, France. Electronic address:
Background: Intracranial meningiomas are the most common benign central nervous system tumors, often managed with elective surgical resection. While outcomes are generally favorable, postoperative management remains variable, particularly regarding routine Intensive-Care Units (ICU) admission. Given increasing pressure on critical care resources, identifying patients who truly require ICU-level monitoring is essential.
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