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The AO Spine Knowledge Forums are independent expert-driven global study groups dedicated to improving patient care by publishing evidence-based recommendations and conducting high-impact clinical studies. Five Knowledge Forums represent 6 spine pathologies: tumor, deformity, spinal cord injury, degeneration, trauma, and infection. A summary highlighting their most impactful research achievements over the past 10 years is provided. The results illustrate the critical clinical role of these independent Knowledge Forums.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149163 | PMC |
http://dx.doi.org/10.1177/21925682251343521 | DOI Listing |
J Glaucoma
September 2025
Harvard Medical School, Boston, MA.
Purpose: Large language models (LLMs) can assist patients who seek medical knowledge online to guide their own glaucoma care. Understanding the differences in LLM performance on glaucoma-related questions can inform patients about the best resources to obtain relevant information.
Methods: This cross-sectional study evaluated the accuracy, comprehensiveness, quality, and readability of LLM-generated responses to glaucoma inquiries.
BMJ Public Health
September 2025
School of Public Health, University of Sydney, Sydney, New South Wales, Australia.
Introduction: Curbing adolescent vaping is a public health priority and little evidence exists examining protective factors. Using a strength-based approach, this study explored the relationship between adolescent vaping health perceptions and vaping use.
Methods: Cross-sectional data from 9000 Australian adolescents aged 14-17 years recruited via multiple online panels as part of the Generation Vape Study were used.
Global Spine J
September 2025
Department of Spine Surgery, Orthopaedic Research Group, Coimbatore, India.
JMIR Diabetes
August 2025
1. Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, Fatmawati General Hospital, Jakarta, Indonesia, Jl. RS. Fatmawati Raya, Cilandak Bar., Kec. Cilandak, South Jakarta, ID.
Background: Insulin therapy is crucial for type 2 diabetes mellitus management, with increasing usage in Indonesia, and its effectiveness is well-established. However, prescribing insulin poses various challenges that can impact the effectiveness of insulin. Patient education is crucial for the successful implementation of insulin therapy.
View Article and Find Full Text PDFFront Psychiatry
August 2025
Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Background: Modified electroconvulsive therapy (mECT), the administration of ECT under general anesthesia with muscular relaxation, is indicated for perinatal depression complicated by high severity, psychosis, catatonia, or resistance to conventional therapeutics; however, knowledge gaps remain regarding its effectiveness and safety in depressed patients and its fetal/neonatal risk profile.
Materials And Methods: We conducted a scoping review of the literature describing the effectiveness and safety (maternal, fetal, and neonatal) of mECT for perinatal depression. Online databases were searched (inception to December 31, 2024) to identify clinical trials, observational studies, case series, and case reports that were topically relevant.