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Introduction: Prior studies have demonstrated improved outcomes for admitted children at pediatric-only hospitals (POHs) (e.g. children's hospitals) versus combined pediatric-adult trauma centers (CPACs). However, there is a paucity of data regarding disparities of overall and intensive care unit (ICU) admissions between POHs and CPACs. This study compared POHs versus CPACs, hypothesizing increased overall and ICU admissions at CPACs.
Methods: A retrospective (2017-2021) analysis of the Trauma Quality Improvement Program database was performed, comparing 1-14-y-old patients treated at POHs versus CPACs. The primary outcomes were overall and ICU admissions rates. Secondary outcomes include inpatient complications and mortality. Two separate multivariable logistic regression analyses evaluated associated risk of mortality and risk of complications for those admitted, controlling for age, injury severity score, mechanism of injury, and brain injury.
Results: Of 199,414 children, 110,041 (55.2%) were treated at POHs and 89,373 (44.8%) at CPACs. Patients admitted to POHs were slightly younger (median 7 versus 8 y-old, P < 0.001) and had a decreased yet statistically different median injury severity score (POH: 4 versus CPAC: 5, P < 0.001). CPAC patients had increased overall (77.8% versus 66.2% P < 0.001) and ICU admissions (13.6% versus 6.3%, P < 0.001). POH patients had statistically decreased complications (1.2% versus 1.3%, P = 0.041) and mortality (0.7% versus 0.9%, P < 0.001). However, these findings did not persist on multivariable analysis (complications: P = 0.99; mortality: P = 0.12).
Conclusions: This national analysis demonstrated differences in admission patterns between POHs and CPACs. The higher admission rates at CPACs yet similar associated risk of complications and mortality suggest a potential opportunity for improvement efforts at these centers.
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http://dx.doi.org/10.1016/j.jss.2025.05.003 | DOI Listing |
J Intensive Care
September 2025
German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-Universitat (LMU), University Hospital Grosshadern, Munich, Germany.
Background: Survivors of critical illness frequently face physical, cognitive and psychological impairments after intensive care. Sensorimotor impairments potentially have a negative impact on participation. However, comprehensive understanding of sensorimotor recovery and participation in survivors of critical illness is limited.
View Article and Find Full Text PDFHosp Pediatr
September 2025
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Background: Direct admission can help reduce emergency department crowding, improve patient satisfaction, and decrease costs, yet there is opportunity to improve standardized processes to do so safely and efficiently. We designed and implemented a new process for urgent direct admission (UDA) at our children's hospital with the SMART (specific, measurable, achievable, relevant, time-bound) aim to increase the number of UDAs between transfer to an intensive care unit (ICU) within 12 hours from direct admission by 50% in 12 months.
Methods: We compared unanticipated ICU transfers within 12 hours of admission (outcome) before and after implementing a standardized UDA process.
Crit Care Explor
September 2025
Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Professions, Gainesville, FL.
Objectives Background: Monocyte anisocytosis (monocyte distribution width [MDW]) has been previously validated to predict sepsis and outcome in patients presenting in the emergency department and mixed-population ICUs. Determining sepsis in a critically ill surgical/trauma population is often difficult due to concomitant inflammation and stress. We examined whether MDW could identify sepsis among patients admitted to a surgical/trauma ICU and predict clinical outcome.
View Article and Find Full Text PDFInt Arch Allergy Immunol
September 2025
Background: Anaphylaxis is a life-threatening, systemic allergic reaction. This study aims to compare anaphylactic triggers, clinical presentation and management between elderly (≥65 years old) and non-elderly adults.
Methods: Data from the Cross-Canada Anaphylaxis Registry (C-CARE) from April 2011 to May 2024 was collected, spanning five emergency departments (EDs) and one emergency medical service (EMS) across three Canadian provinces.
J Epidemiol Glob Health
September 2025
Center for Communicable Diseases Control (CDC), Ministry of Health and Medical Education, Tehran, Iran.
Background: Healthcare-associated infections (HCAIs) pose a serious threat to healthcare systems. Accurately determining the incidence of HCAIs is crucial for planning and implementing efficient interventions, as they are associated with a wide range of challenges. The objective of this study was to assess and update the incidence rates of HCAIs in Iran in 2023, using data from the Iranian Nosocomial Infection Surveillance (INIS) system, a nationwide hospital-based surveillance program.
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