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Introduction: The complexity of ramp terminals, coupled with distracted driving (which impairs drivers' abilities and slows reaction time), presents significant challenges to drivers. The safety at interchange ramp terminals, particularly concerning distracted driving crashes, has not been thoroughly investigated. This study develops safety performance functions (SPFs) for fatal-and-injury (FI) distraction-related crashes at ramp terminals in Kentucky between 2018 and 2021.
Method: To account for zero-inflated count data, zero-inflated models, including the zero-inflated negative binomial (ZINB), zero-inflated Conway-Maxwell-Poisson (ZICMP), and zero-inflated heterogeneous Conway-Maxwell-Poisson (ZIHTCMP), were used.
Results: The goodness-of-fit measures indicated that the ZIHTCMP model outperformed the other models. From the developed SPFs, the distance to adjacent ramp terminal (> 800 ft) and presence of traffic signal control were associated with increased FI distraction-related crashes. On the other hand, the presence of a channelizing island at the exit ramp, presence of rumble strips at the exit ramp, presence of an exclusive left-turn on the crossroad (or major road), and higher number of lanes at the exit ramp were associated with reduced FI distraction-related crashes. An in-depth investigation of distraction-related crashes at the high-crash ramp terminal locations revealed that "in-vehicle distraction" and "cognitive distraction" were the most common incidents.
Practical Applications: Based on the study findings, several targeted countermeasures were proposed to improve safety related to distracted driving at ramp terminals, such as designing ramp terminals within 800 ft of each other, installation of retroreflective backplates on signal heads, and installation of optical speed bars on the exclusive right-turning lanes on crossroads.
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http://dx.doi.org/10.1016/j.jsr.2025.02.008 | DOI Listing |
Sci Adv
August 2025
Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
The essential architectural protein HMGB1 increases accessibility of nucleosomal DNA and counteracts the effects of linker histone H1. However, HMGB1 is less abundant than H1 and binds nucleosomes more weakly, raising the question of how it competes with H1. Here, we find that HMGB1 increases nucleosomal DNA accessibility without displacing H1.
View Article and Find Full Text PDFFront Vet Sci
July 2025
Division of Clinical Radiology, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Objective: The objective of this study was to establish a non-contrast enhanced MR angiography (NC-MRA) sequence for the equine foot (EF) using a post-mortem angiography model.
Materials And Methods: Time-of-flight (TOF) sequences were tested using variable parameter settings and 3 slice orientations during vascular perfusion of frozen-thawed cadaver EF with paraffine oil. Transverse and dorsal orientations were planned perpendicular or parallel to the sublamellar vascular plexus at the dorsal aspect of P3, or approximately perpendicular to the coronary plexus.
Introduction: The complexity of ramp terminals, coupled with distracted driving (which impairs drivers' abilities and slows reaction time), presents significant challenges to drivers. The safety at interchange ramp terminals, particularly concerning distracted driving crashes, has not been thoroughly investigated. This study develops safety performance functions (SPFs) for fatal-and-injury (FI) distraction-related crashes at ramp terminals in Kentucky between 2018 and 2021.
View Article and Find Full Text PDFCardiol Res
April 2025
Cardiology Department, Hospital Universitario de La Princesa, Universidad Autonoma de Madrid, Madrid, Spain.
Background: The detection of underlying paroxysmal atrial fibrillation (AF) in patients with cryptogenic stroke (CS) can be challenging, and there is great interest in finding predictors of its hidden presence. The recent development of sophisticated software has enhanced the diagnostic and prognostic performance of the 12-lead electrocardiogram (ECG). Our aim was to assess the additional role of a computer-assisted ECG analysis in identifying predictors of AF in patients with CS.
View Article and Find Full Text PDFCell Rep
January 2025
Center for the Neural Basis of Cognition, Carnegie Mellon University, Pittsburgh, PA, USA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA; Translational Neuroscience Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: ahmarise
Understanding how corticostriatal circuits mediate behavioral selection and initiation in a naturalistic setting is critical to understanding behavior choice and execution in unconstrained situations. The central striatum (CS) is well poised to play an important role in these spontaneous processes. Using fiber photometry and optogenetics, we identify a role for CS in grooming initiation.
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