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Vector-borne diseases, particularly arboviral diseases transmitted by mosquitoes (e.g. dengue, Zika and chikungunya), have (re)emerged globally with increasing prevalence and severity. Climatic and environmental changes have resulted in significant expansion of the geographical distribution of Aedes mosquito vectors to unprecedented levels, creating optimal conditions for their introduction and establishment in new areas, especially in Africa. The prevention of Aedes-borne diseases relies heavily on controlling vector populations. However, the global resurgence of dengue underscores the limitations of current vector control tools in preventing epidemics, highlighting the urgent need for affordable, scalable and community-based vector control measures to address Aedes-borne diseases and urban mosquito vectors (e.g. Aedes spp. and Anopheles stephensi), with the overall aim to improve public health and well-being. In this report, we summarize the main outcomes of the "International conference on advances in surveillance and control methods for Aedes-borne diseases and urban vectors" held in Dar es Salaam, Tanzania, 26-28 August 2024. The conference aimed to facilitate knowledge exchange, promote collaborative research and drive innovation in the surveillance and control of Aedes-borne diseases in Africa. Key objectives included reviewing the performance of new tools and technologies for Aedes control, and fostering inter-sectoral and international collaborations to strengthen public health measures against mosquito-borne diseases. The event was attended by more than 200 participants from 20 nationalities/countries and was streamed live online, with 321 virtual accesses recorded during the 3-day event.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142953 | PMC |
http://dx.doi.org/10.1186/s13071-025-06838-4 | DOI Listing |
Pestic Biochem Physiol
November 2025
Department of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA. Electronic address:
The global rise of mosquito-borne diseases and widespread resistance to existing insecticides highlight the urgent need for novel, field-relevant mosquitocides. Here, we report the development and validation of a high-throughput, in vivo screening assay capable of evaluating adult mosquito toxicity across large chemical libraries. Utilizing a 96-well plate format, this assay enables simultaneous testing of hundreds of compounds per run using both net and filter paper substrates, with direct measurement of adult mosquito knockdown and mortality via tarsal contact - an exposure route highly relevant to real-world vector control tools such as long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS).
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Arbovirus and Entomology Department, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
This study addresses the pressing global health burden of mosquito-borne diseases by investigating the application of Convolutional Neural Networks (CNNs) for mosquito species identification using wing images. Conventional identification methods are hampered by the need for significant expertise and resources, while CNNs offer a promising alternative. Our research aimed to develop a reliable and applicable classification system that can be used under real-world conditions, with a focus on improving model adaptability to unencountered devices, mitigating dataset biases, and ensuring usability across different users without standardized protocols.
View Article and Find Full Text PDFClin Microbiol Rev
September 2025
Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.
SUMMARYDengue is an acute mosquito-borne viral disease that is highly prevalent throughout the tropical world. The geographic footprint of the four dengue viruses (DENV-1 to -4) that cause this disease and their mosquito vector is expanding, extending into North America and Mediterranean Europe. Furthermore, although dengue has historically been a disease that disproportionately affects children, changing population demographics and increasing travel to and from the tropics have contributed to a growing incidence in adults.
View Article and Find Full Text PDFVet Rec
September 2025
APHA.
With the geographical distribution of West Nile virus expanding, there is growing concern about the potential for an incursion to the UK. Here, Fleur Whitlock, Richard Newton, Simon King, Andra-Maria Ionescu and Sara Higgins provide a timely reminder of key aspects of the virus' biology.
View Article and Find Full Text PDFJ Med Virol
September 2025
Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
The pathogenesis of dengue remains complex and incompletely understood. One proposed mechanism involves the virus evading host immune responses through the upregulation and/or secretion of immune-inhibitory molecules. This study investigates the association between plasma levels of soluble human leukocyte antigen G (sHLA-G), a known immunoregulatory molecule, and dengue severity in hospitalized patients.
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