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Objective: The objectives were to (1) assess the frequency of adolescents potentially at risk for sleep-disordered breathing (SDB) as measured by the paediatric sleep questionnaire (PSQ), and (2) investigate any associations between adolescents at risk for SDB and specific dentofacial characteristics extracted from standard orthodontic records.
Methods: Patients aged 6-16 years, receiving orthodontic treatment, were included. All patients had completed the Danish version of PSQ. Based on the PSQ score, the sample was divided into two groups: high-risk and low-risk of SDB. Features related to clinical examination, dental cast analysis and cephalometric assessment were tested for intergroup differences between the high-risk and the low-risk PSQ groups. Student's t-tests, Chi-square test and linear mixed models were computed to compare the dentofacial variables of the two groups.
Results: A total of 246 patients were included (94 boys and 152 girls, mean age 12.7 ± 2.1). The prevalence of patients with a PSQ score indicating a high risk of SDB was 6.5% (n = 16). The mean values of A-N-Pog, A-N-B and S-N-A were significantly larger in the high-risk group compared to the low-risk group by 1.5° (p = 0.037), 1.3° (p = 0.043) and 2.0° (p = 0.050) respectively. When considering the results from a linear mixed model, A-N-Pog and A-N-B showed statistically significant differences between the two groups.
Conclusions: Six percent of patients presented a high risk of SDB. The present study showed that adolescents at a high risk for SDB displayed more sagittal skeletal discrepancies compared to those at low risk. This study's strength lies in its large and representative sample of orthodontic patients, enabling comprehensive analysis of SDB-related factors, yet the small number of high-risk SDB cases detected constitutes a statistical limitation, highlighting the need for further research with an even larger sample.
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http://dx.doi.org/10.1111/joor.14047 | DOI Listing |
Clin Cosmet Investig Dent
September 2025
Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.
Purpose: Mouth breathing is an associated or characteristic feature of sleep-disordered breathing (SDB), not a direct cause. This study aims to investigate whether mouth-breathing children in Indonesia have a higher risk of SDB, as assessed by the Pediatric Sleep Questionnaire (PSQ) questionnaire.
Patients And Methods: A cross-sectional study was conducted in three public elementary schools in Bandung (SDN 001 Merdeka, SDN 062 Ciujung, and SDN 054 Tikukur), involving 343 children aged 8-9 years (193 boys, 150 girls).
JAMA Cardiol
September 2025
Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Importance: Sleep disordered breathing (SDB) is a well-established contributor to cardiovascular morbidity, mediated by intermittent hypoxemia, autonomic dysregulation, and endothelial dysfunction. Patients with hypertrophic cardiomyopathy (HCM) may be especially at risk for SDB, but the clinical impact of SDB in this population remains unclear.
Objective: To define the prevalence and subtypes of SDB in HCM and examine their association with echocardiographic parameters and cardiac biomarker expression.
Pediatr Neurol
August 2025
Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada. Electronic address:
Background: Perinatal stroke is a leading cause of cerebral palsy and lifelong neurological disability and a potential risk factor for sleep-disordered breathing (SDB).
Methods: We examined the risk for SDB and associated psychosocial outcomes among 77 children with perinatal stroke. Caregivers completed validated questionnaires evaluating their children's sleep (Pediatric Sleep Questionnaire), mental health (Behavior Assessment System for Children, Third Edition [BASC-3]), and quality of life (Pediatric Quality of Life Inventory [PedsQL]) as well as the psychosocial impact on themselves (Parental Outcome Measure [POM]).
Curr Opin Pulm Med
August 2025
Department of Physiotherapy, School of Health Sciences, The University of Melbourne.
Purpose Of Review: Sleep disordered breathing (SDB) is a direct consequence of tetraplegic spinal cord injury (SCI), is highly prevalent in both tetraplegia and paraplegia, and is associated with worse daytime functioning and reduced quality of life. Despite this, most people with SCI are undiagnosed and untreated for the disorder. This narrative review summarises research from the last 5 years on the epidemiology, pathophysiology, and consequences of SDB in SCI, as well as the current approaches to screening, diagnosis, and treatment of SDB in this population.
View Article and Find Full Text PDFJMIR Cancer
August 2025
Pfizer Pharma GmbH, Friedrichstr. 110, Berlin, 10117, Germany, 49 15152377580.
Background: Patients with breast cancer frequently experience significant uncertainty, prompting them to seek detailed, personalized, and reliable medical information to enhance adherence to prescribed treatments, medications, and recommended lifestyle adjustments. Although high-quality information exists within oncology guidelines and patient-oriented resources, the provision of tailored responses to individual patient queries remains challenging, especially for non-English-speaking populations.
Objective: This study aims to evaluate the potential of an artificial intelligence-driven chatbot, specifically leveraging ChatGPT (GPT-4; OpenAI) combined with retrieval-augmented generation, to deliver personalized answers to complex breast cancer-related patient questions in German.