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| http://dx.doi.org/10.1016/j.brainres.2025.149685 | DOI Listing |
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Background: The study aimed to adapt a stress and well-being intervention delivered via a mobile health (mHealth) app for Latinx Millennial caregivers. This demographic, born between 1981 and 1996, represents a significant portion of caregivers in the United States, with unique challenges due to higher mental distress and poorer physical health compared to non-caregivers. Latinx Millennial caregivers face additional barriers, including higher uninsured rates and increased caregiving burdens.
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Diarrhoea due to rotavirus remains a significant cause of child mortality in developing regions. Caregivers' perspectives on the social determinants of gastroenteritis and childhood vaccination, including the rotavirus vaccine, were explored through focus group discussions in Ethiopia (n = 6), Kenya (n = 14), and Malawi (n = 10), using a combination of thematic and framework analysis approaches. The results show that diarrhoea was perceived to be a burden in all three countries, particularly among infants, due to challenges in WASH (water, sanitation, and hygiene) infrastructures and poverty.
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The environmental resistance exhibited by microorganisms is concerned with their ability to withstand and adapt to an array of detrimental environmental conditions, with their survival and reproductive success being threatened. Within the realm of biotechnology, which emphasizes stress resistance, a critical role in bacterial adaptive strategies to environmental fluctuations is assumed to be in the periplasmic space. An innovative methodology to augment bacterial tolerance to stress by employing a mucin-mimetic collagen analogue, designated as S1552 (which is secreted into the periplasmic compartment), is introduced by this investigation.
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