Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objectives: To investigate the effects of sodium fluoride (NaF), casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and titanium tetrafluoride (TiF4) on the prevention of demineralization in irradiated bovine enamel and dentin in vitro.
Methodology: The enamel and dentin sample blocks were subjected to 50 Gy of radiation and divided into five groups (n=13): the deionized distilled water group, the NaF group, the CPP-ACP group, the NaF + CPP-ACP group, and the TiF4 group. After being treated with various materials for 30 minutes, the samples were remineralized for 12 hours and demineralized for 48 hours. The samples were then evaluated by scanning electron microscope (SEM), atomic force microscope (AFM), energy dispersive spectrometer (EDS), and transverse microradiography (TMR). Data were analyzed by ANOVA and the Kruskal-Wallis H test (α=0.05).
Results: SEM and TMR indicated that the TiF4 group promoted more mineral deposits on the enamel and dentin samples, showing the least mineral loss and the lowest lesion depth. AFM results showed that the NaF + CPP-ACP group had the lowest enamel roughness (p<0.05), whereas the TiF4 group showed the lowest roughness in dentin samples (p<0.05). EDS showed that titanium (Ti) was deposited on the surface of the TiF4 group samples, whereas the NaF + CPP-ACP group more greatly aggregated fluorine.
Conclusion: TiF4 significantly impacted the prevention of demineralization in irradiated dental hard tissues. Combining NaF and CPP-ACP more effectively prevented demineralization than either agent used alone.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12218195 | PMC |
| http://dx.doi.org/10.1590/1678-7757-2024-0524 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Modulation of Prickle2 Expression to Facilitate Dentine Formation: A Laboratory Investigation.
Int Endod J
September 2025
Department of Biochemistry, School of Dentistry, IHBR, Kyungpook National University, Daegu, South Korea.
Aim: Prickle planar cell polarity (PCP) protein 2 (Prickle2) encodes a homologue of Drosophila prickle and is involved in the non-canonical Wnt/PCP signalling pathway. However, its exact role in dentinogenesis remains unclear. Dentinogenesis, a key process in tooth morphogenesis, involves the patterned arrangement of odontoblasts and the formation of dentine matrix along the pulp cavity.
View Article and Find Full Text PDFSynergistic Effect of Enzymatic Deproteinization and Surface Pre-Reacted Glass Ionomer "SPRG" Fillers in self-etch adhesives: Boosting Anti-Demineralization and ABRZ.
J Dent
September 2025
Department of Restorative Dentistry, Faculty of Dentistry, Malaya University, Kuala Lumpur, Malaysia. Electronic address:
Objectives: to evaluate the effect of smear-layer deproteinization using papain gel and SPRG-adhesive on marginal-gap, anti-demineralization of enamel and dentin after chemical pH cycling and assess acid-base resistance zone (ABRZ) characteristics.
Methods: Cylindrical cavities were prepared cervically in thirty-two extracted premolars. Teeth were divided into two pretreatment groups (n=16); deproteinization with papain enzyme gel (Papacarie Due, Brazil) for 60 second, and no-deproteinization.
Comparative evaluation of fracture resistance of re-attached teeth using self-adhesive bioactive flowable composite after preconditioning the fractured coronal fragments with different remineralizing agents.
F1000Res
September 2025
Associate professor, Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi, wardha, Maharashtra, 442001, India.
One of the common forms of dental injury is anterior crown fractures, which mainly affect teenagers and young adults. Fractures of the coronal portion of the permanent incisors characterize 18-22% of total traumatic injuries to dental hard tissues, of which 96% of them comprise the maxillary incisors. An uncomplicated fracture of the crown is one of the most common types of dental traumatic injury.
View Article and Find Full Text PDFMulti-modal comparison of murine and human incisal dentin-enamel junctions.
Acta Biochim Pol
September 2025
Department of Biomedical Engineering, UConn Health Center, Farmington, CT, United States.
Human and mouse incisors are both primarily composed of dentin and enamel, which meet at an interface called the dentin-enamel junction (DEJ). However, incisors in the two species have very different growth patterns, structures, and loading requirements. Since the DEJ is responsible for minimizing cracking at this at-risk interface between mechanically dissimilar dentin and enamel, its structure is expected to be significantly different between humans and mice.
View Article and Find Full Text PDFPerformance of nitric acid and mineral enriched system versus phosphoric acid and universal adhesive in cervical carious lesions: a randomized clinical trial.
BDJ Open
September 2025
Professor of Conservative Dentistry, Conservative Dentistry Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Objective: To evaluate the clinical performance of nitric acid associated with a mineral-enriched adhesive system compared to the conventional approach of phosphoric acid and a universal adhesive in cervical carious lesion restorations.
Materials And Methods: Twenty-six individuals with 44 cervical anterior carious lesions were randomized into two equal parallel groups. The intervention group received a nitric acid etch (Clean and Boost dentin enamel cleanser, Vista Apex, USA) in conjunction with a mineral-enriched adhesive and a flowable composite liner (RE-GEN, Vista Apex, USA).