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Background: Use of nonoperative management for uncomplicated appendicitis is increasing. Recurrent appendicitis is only one measure of successful nonoperative management. We examined health care utilization and exposure to medical imaging between patients postappendectomy and those with an in situ appendix over the year after initial diagnosis. We hypothesized that nonoperative management would result in greater health care utilization than operative management in the year following index diagnosis.
Methods: Using MarketScan, a commercial and fee-for-service Medicare claims database, we extracted patients presenting to the emergency department (ED) with acute appendicitis and without perforation from 2017 to 2021, and either underwent appendectomy during index presentation or nonoperative treatment. We examined differences in abdominal pain related health care utilization within 1-year including ED visits, hospitalizations, and abdominal computed tomography (CT) scans associated with the most common causes of ED presentation for abdominal pain.
Results: Of 26,588 patients presenting with uncomplicated appendicitis (female, 50.4%; mean [SD] age, 37.9 [15.3] years; mean [SD] Elixhauser comorbidity index, 0.8 [1.2]), 24,102 (90.6%) underwent appendectomy. At 1 year, 2,544 (9.6%) represented to the ED with an abdominal pain and/or appendicitis related diagnosis. Of nonoperatively managed patients, 78 (3.1%) underwent appendectomy for recurrent appendicitis at a median of 70 days, and 396 (15.9%) represented to the ED but did not undergo appendectomy. Emergency department visits, subsequent hospitalization, and abdominal CT scans were more common in the nonoperative group. After adjusting for patient sex, age, and Elixhauser comorbidity index, patients managed nonoperatively were approximately twice as likely (relative risk [RR], 2.10 [1.90-2.31]) to represent to the ED, be hospitalized (RR, 2.32 [1.94-2.76]), or undergo a CT scan (RR, 1.87 [1.68-2.08]) within 1 year.
Conclusion: After adjusting for baseline characteristics, nonoperative management of uncomplicated appendicitis was associated with representation to the ED, rehospitalization, and repeat CT imaging.
Level Of Evidence: Therapeutic/Care Management; Level III.
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http://dx.doi.org/10.1097/TA.0000000000004682 | DOI Listing |
Obesity (Silver Spring)
September 2025
Division of Hematology, Oncology, and Palliative Care, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Objective: From October 18-20, 2022, the National Institutes of Health held a workshop to examine the state of the science concerning obesity interventions in adults to promote health equity. The workshop had three objectives: (1) Convene experts from key institutions and the community to identify gaps in knowledge and opportunities to address obesity, (2) generate recommendations for obesity prevention and treatment to achieve health equity, and (3) identify challenges and needs to address obesity prevalence and disparities, and develop a diverse workforce.
Methods: A three-day virtual convening.
Stroke
September 2025
Department of Medicine, University of Melbourne, Parkville, Victoria, Australia. (V.Y., B.C.V.C., L.C., L.O., M.W.P.).
Background: To assess the efficacy and safety of tenecteplase in patients presenting within 24 hours of symptom onset with a large vessel occlusion and target mismatch on perfusion computed tomography.
Methods: ETERNAL-LVO was a prospective, randomized, open-label, blinded end point, phase 3, superiority trial where adult participants with a large vessel occlusion, presenting within 24 hours of onset with salvageable tissue on computed tomography perfusion, were randomized to tenecteplase 0.25 mg/kg or standard care across 11 primary and comprehensive stroke centers in Australia.
Dan Med J
August 2025
Department of Clinical Medicine, Aarhus University.
Introduction: Reverse total shoulder arthroplasty is a well-established treatment for patients with rotator cuff tear arthropathy. The outcome after reverse total shoulder arthroplasty has been investigated in several studies and national registries. However, the treatment has not been compared to non-surgical treatment.
View Article and Find Full Text PDFDan Med J
August 2025
Research Unit for General Practice, Department of Public Health, University of Southern Denmark.
Introduction: In various countries, an increasing proportion of general practitioner (GP) referrals is returned by hospitals. We aimed to uncover the causes and consequences of referral returns from the perspective of GP liaisons.
Methods: Individual interviews with 20 GP liaison officers from various departments in Southern Denmark, serving 1.