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Introduction: The varicella zoster virus, which also causes chicken pox in unvaccinated individuals, is the cause of herpes zoster. Vaccinated individuals with partial protection acquired against the virus during a previous chicken pox episode may be susceptible to herpes zoster. When affected by chicken pox, the virus lodges in the posterior nerve root ganglion. From then on, anytime the patient encounters a decrease in cell-mediated immunity during their lifetime, the patient is at a risk of developing an acute eruption that appears like tense vesicles and occurs in groups with surrounding erythema. Typically, the eruption is entirely unilateral and is restricted to a single neural segment. Paraesthesia and intense pain in the afflicted neural segment are the most common consequences of herpes zoster and might appear after the skin eruptions. This pain can last for several months even after the eruption has healed.
Methodology: This case was treated at the OPD of Dr. D.Y. Patil Homoeopathic Medical College & Research Centre, Pune, India. A 67-year-old male patient was diagnosed with postherpetic neuralgia (PHN). During one month of regular treatment, all the complaints were resolved.
Result: All of the problems were resolved after prescribing individualised homoeopathic medication over a month of routine follow-up visits. The patient's problems with his bodily and mental well-being were resolved. The patient's visual analogue scale score, used to assess pain, dropped to 0 from 9.
Conclusion: We may infer that tailored homoeopathic therapy is beneficial in treating postherpetic complications based on the favourable outcome shown in this case.
Keywords: Postherpetic Neuralgia, Herpes Zoster, Varicella-zoster virus, Homoeopathy, Arsenicum album, Ranunculus bulbous, Totality of symptoms, Case report.
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Clin Transl Oncol
September 2025
Ophthalmology Unit, Cannizzaro Hospital, 95126, Catania, Italy.
Antibody-drug conjugates (ADCs) represent a promising therapeutic approach in gynecologic cancers, particularly ovarian and cervical malignancies. Agents such as mirvetuximab soravtansine, and tisotumab vedotin, targeting folate receptor alpha and tissue factor, respectively, reported clinical efficacy in patients with limited options. However, their use is associated with ocular toxicities, including keratopathy, blurred vision, and dry eye, which may impact adherence and quality of life.
View Article and Find Full Text PDFPharmacoecon Open
September 2025
Department of Pharmacy, The Second Affiliated Hospital of Army Medical University, No.83 Xinqiao Central Street, Shapingba District, Chongqing, 400037, China.
Objective: Two vaccines against herpes zoster (HZ) are currently authorized for use in China: the adjuvanted recombinant zoster vaccine (RZV) and live-attenuated Zoster Vaccine Live (ZVL). The significant disparities in prices and efficacy between the two vaccines necessitate an evaluation of their relative value in order to make an informed choice. This study aimed to evaluate the comparative cost effectiveness of RZV, ZVL, and no vaccination for older adults at different ages from the societal perspective.
View Article and Find Full Text PDFAustralas J Dermatol
September 2025
Sydney School of Medicine, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
We report a case of zosteriform PCMZL presenting in a T3-T4 dermatomal distribution not previously described in the literature. Although the varicella zoster virus was not detected in this case, late diagnosis of the acute eruption of zoster or even preceding zoster 'sine herpete' cannot be excluded as antigenic triggers.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Family and Community Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Herpes zoster (HZ) is a reactivation of the varicella-zoster virus. It is a common infection, especially among patients with diabetes mellitus (DM). This study aimed to assess the awareness and uptake of the HZ vaccine, as well as their determinants, among patients with diabetes DM in the Aseer Region, Saudi Arabia.
View Article and Find Full Text PDFLupus Sci Med
September 2025
Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Background: SLE has increased risk of invasive pneumococcal disease due to immune dysregulation and immunosuppression. European Alliance of Associations for Rheumatology recommendations suggest sequential vaccination with conjugate vaccine, followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23). However, data on immunogenicity of sequential vaccination in SLE are limited.
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