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Over-supporting and under-supporting of the roadway perimeter rock in the mining process will affect the support effect, so the existing roadway perimeter rock support needs to be analysed, and the support structure parameters need to be adjusted accordingly. In order to study the deformation characteristics of the roadway surrounding rock, this article adopts FLAC3D software to simulate the stress distribution and deformation characteristics of the roadway surrounding rock under the existing anchor support, and analyses the test results of the support structure parameters based on mathematical methods. The results show that the existing support situation can improve the surrounding rock stress state, reduce the degree of stress concentration in the surrounding rock, effectively reduce the range of the plastic zone, and reduce the deformation value of the surrounding rock in the roadway, but it cannot effectively reduce the range of its plastic zone. Through orthogonal test, using extreme difference analysis, the primary and secondary order of the influence of the main control factors of the roof roadway on the total deformation of the roadway was obtained as follows: the thickness of the sprayed slurry > the anchor spacing > the length of the anchors = the distance between the rows of anchors. The roof of the roadway is: Spray thickness > Anchor spacing > Anchor length > Anchor row spacing. For the left gang of the roadway, it is: Spray thickness > Anchor spacing > Anchor row spacing > Anchor length, and for the right gang of the roadway, it is: Spray thickness > Anchor row spacing > Anchor length > Anchor spacing. For the total deformation of the roadway in the vein of the ore layer, the primary and secondary order of the influence of the two gangs is: the thickness of the spray slurry > anchor length > anchor spacing > anchor row spacing, and for the top plate of the roadway is: the thickness of the spray slurry > anchor length > anchor row spacing > anchor spacing. When the displacement of the roadway exceeds the permissible amount, the support parameters can be adjusted in the order of the degree of influence of each of the main control factors mentioned above. The results of the study can provide reference significance for the design and optimization of support for similar mines.
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http://dx.doi.org/10.1177/00368504251346393 | DOI Listing |
Sci Total Environ
September 2025
Human Foods Program, U.S. Food and Drug Administration, College Park, MD, USA.
Cattle are a reservoir for the zoonotic human foodborne pathogen Shiga toxin-producing Escherichia coli (STEC), the causative agent of many disease outbreaks associated with contaminated fresh leafy greens. Concentrated animal feeding operations (CAFOs) housing cattle generate fugitive dust, however the potential risk of STEC movement by means of the aerosolized dust is not well known. In this investigation, we used metagenome sequencing of air samples collected in an agricultural setting to investigate airborne transfer of STEC from a large CAFO to the surrounding area.
View Article and Find Full Text PDFOncogene
September 2025
Division of Neurosurgery, Children's Hospital Los Angeles, Los Angeles, CA, USA.
It has become evident from decades of clinical trials that multimodal therapeutic approaches with focus on cell intrinsic and microenvironmental cues are needed to improve understanding and treat the rare, inoperable, and ultimately fatal diffuse intrinsic pontine glioma (DIPG), now categorized as a diffuse midline glioma. In this study we report the development and characterization of an in vitro system utilizing 3D Tumor Tissue Analogs (TTA), designed to replicate the intricate DIPG microenvironment. The innate ability of fluorescently labeled human brain endothelial cells, microglia, and patient-derived DIPG cell lines to self-assemble has been exploited to generate multicellular 3D TTAs that mimic tissue-like microstructures, enabling an in- depth exploration of the spatio-temporal dynamics between neoplastic and stromal cells.
View Article and Find Full Text PDFEcotoxicol Environ Saf
September 2025
CanmetMINING, Natural Resources Canada, Ottawa, ON, Canada. Electronic address:
Acid mine drainage (AMD) is a serious environmental problem at legacy and active mine sites around the world. Climate associated drought and rewetting events can increase the severity of AMD impacts through oxidation and release of stored metal(loid)s and acidity from contaminated sediments. The area surrounding Sudbury, Ontario, with its massive mining and smelting complexes, appears especially vulnerable to drought-driven effects.
View Article and Find Full Text PDFSci Rep
September 2025
Yunnan Provincial Transportation Planning and Design Research Institute Co., Ltd, Kunming, 650041, China.
Due to the high construction efficiency and low cost, double-arch tunnels without middle drift has been gradually promoted in engineering in recent years. However, the excavation characteristics of the left and right tunnels are easy to cause structural disturbance and deformation out of control. In particular, the surrounding rock disturbance of the front tunnel caused by the construction of the secondary tunnel often leads to lining cracking and structural instability.
View Article and Find Full Text PDFACS Omega
August 2025
Key Laboratory of Safe and Effective Coal Mining, Ministry of Education of China, Anhui University of Science and Technology, Huainan 232001, China.
To investigate the failure behavior and cracking mechanisms in surrounding rock, a true triaxial experimental system and digital imaging were employed to perform compression tests on sandstone specimens containing preexisting flaws. Experimental results revealed the propagation characteristics of microfractures under stress concentration conditions and their correlation with failure patterns. Furthermore, a fracture propagation model was implemented to evaluate the susceptibility of surrounding rock to failure.
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