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http://dx.doi.org/10.47895/amp.v59i5.13391 | DOI Listing |
Food Funct
September 2025
College of Food Science, Southwest University, Chongqing, 400715, China.
Bifidobacteria are naturally found in the human gut and quickly establish dominance shortly after birth, playing a crucial role in the development and stability of the infant gut microbiota. A growing body of research suggests that host and environmental factors shape the colonization and the relative abundance of bifidobacteria in the infant gut during early life. Understanding the factors that influence bifidobacterial colonization and maintaining normal colonization levels are keys to ensuring gut health.
View Article and Find Full Text PDFHematology
December 2025
Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, People's Republic of China.
Background: Childhood leukaemia remains a major global health challenge and its impact varies significantly by region. Understanding the patterns of incidence, mortality, prevalence, and disability-adjusted life years (DALYs) is crucial for crafting effective public health initiatives and enhancing care outcomes, especially in regions with constrained resources.
Methods: This study evaluates the worldwide, regional, and country-specific effects of childhood leukemia between 1990 and 2021, leveraging data from the Global Burden of Disease (GBD) initiative.
Front Pediatr
August 2025
Department of Neonatal Research, Inova Health Services, Falls Church, VA, United States.
Introduction: Neonatal sepsis is a dysregulated immune response to bloodstream infection causing serious disease and death. Our review seeks to integrate the knowledge gained from studies of multiple molecular methods- such as genomics, metabolomics, transcriptomics, and the gut microbiome- in the setting of neonatal sepsis that may improve the diagnosis, classification, and treatment of the disease. Sepsis claims over 200,000 lives annually worldwide and remains a top 10 cause of infant mortality in the US.
View Article and Find Full Text PDFNurs Child Young People
September 2025
Vaccine Preventable Disease Programme, Public Health Wales, Cardiff, Wales.
Measles is a highly infectious, notifiable, viral disease that is commonly contracted in childhood and associated with a characteristic rash. Most children and young people who contract measles make a full recovery, but measles infection is associated with rare but serious complications in vulnerable groups, such young infants, immunocompromised individuals and pregnant women. Vaccination is the most effective way to prevent measles infection, but uptake of the measles, mumps and rubella (MMR) vaccine in the UK has fallen short of the vaccine coverage required to provide herd immunity and prevent measles outbreaks.
View Article and Find Full Text PDFNat Aging
September 2025
Aging Biomarker Consortium (ABC), Beijing, China.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.
View Article and Find Full Text PDF