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Introduction: Continuous improvements in the field of adhesive dentistry have led to the introduction of various materials that have the potential to be used as orthodontic adhesives. One such light-cure orthodontic adhesive is the U-Bond™ Ortho, which clinically exhibits optimum bonding strength.
Objective: The aim of this cross-arch split-mouth prospective study was to evaluate the bonding failure rate along with the bracket survival time of U-Bond™ Ortho as compared with Transbond™ XT adhesive material, over an observation period of six months.
Material And Methods: 36 consecutive patients (16 males and 20 females; mean age 22.44 years) fulfilling the selection criteria were included in the study. A total of 720 brackets were bonded equally using Transbond™ XT and U-Bond™ adhesive, which were analyzed for bracket failure rate, using the Chi-square test or Fischer test, and mean bracket survival time using Kaplan-Meier analysis.
Results: The overall bracket failure rate was 3.6% (2.8% and 4.4% for Transbond™ XT and U-Bond™ respectively). The results were statistically non-significant when both adhesive materials were compared for differences in bonding failure rate and mean bracket survival time in the maxillary and mandibular arches, and anterior and posterior segments, although gender-based differences were statistically significant.
Conclusion: Both Transbond™ XT and U-Bond™ Ortho exhibited similar clinically acceptable performances in terms of bonding failure rate and bracket survival time.
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http://dx.doi.org/10.1590/2177-6709.30.2.e2524214.oar | DOI Listing |
PLoS Genet
September 2025
MIVEGEC, University of Montpellier, CNRS, IRD, Montpellier, France.
Cytoplasmic Incompatibility (CI) causes embryonic lethality in arthropods, resulting in a significant reduction in reproductive success. In most cases, this reproductive failure is driven by Wolbachia endosymbionts through their cifA/cifB gene pair, whose products disrupts arthropod DNA replication during embryogenesis. While a cif pair has been considered a hallmark of Wolbachia, its presence and functional significance in other bacterial lineages remains poorly investigated.
View Article and Find Full Text PDFPLoS One
September 2025
University of Health and Allied Sciences, Volta Region-Ho, Ghana.
Introduction: The alarming rate of drug-resistant tuberculosis (DR-TB) globally is a threat to treatment success among positive tuberculosis (TB) cases. Studies aimed at determining the prevalence, trend of DR-TB and socio-demographic and clinical risk factors contributing to DR-TB in the four regions of Ghana are currently unknown. This study sought to determine the prevalence and trend of DR-TB, identify socio-demographic and clinical risk factors that influence DR-TB, and analyse the relationship between underweight and adverse drug reactions and treatment outcomes among DR-TB patients in four regions of Ghana.
View Article and Find Full Text PDFJ Nephrol
September 2025
Institute of Nephrology, Madras Medical College, Chennai, India.
Background: IgA nephropathy is a disease with a highly variable natural history, for which there is an increasing understanding of the role of complement activation in its pathogenesis and progression. We aimed to assess the clinical and prognostic implications of C4d staining in the kidney biopsy of IgA nephropathy patients.
Methods: This was a retrospective observational study wherein the medical records of IgA nephropathy patients were reviewed and baseline characteristics, kidney biopsy findings, treatment response and follow-up data were noted.
J Interv Card Electrophysiol
September 2025
Federal University of Minas Gerais, R. Alfredo Balena, 190, Santa Efigênia, Belo Horizonte, Brazil.
Background: Chagas heart disease (ChD) is a significant public health concern in Latin America, contributing to a high incidence of sudden cardiac death (SCD). Despite advances in heart failure treatment, management of Chagas cardiomyopathy has not progressed accordingly. While ICDs are effective for primary and secondary prevention in other conditions, patients with ChD often experience more frequent episodes of ventricular tachycardia, and ICD use may provide a negative impact and increase mortality.
View Article and Find Full Text PDFArch Orthop Trauma Surg
September 2025
Adult Reconstruction and Joint Replacement Service, Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Background: Differentiating periprosthetic joint infections (PJI) from aseptic failure is challenging in total joint arthroplasty. To date, there is no consensus about the most accurate criteria to diagnose PJI. The current study compares common diagnostic PJI criteria.
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