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Contemporary physical activity (PA) strategies emphasise the PA needs of sedentary and inactive groups, with less emphasis placed on physically active groups. Understanding the needs of physically active groups is important in helping people to keep active. This study investigated the perspectives and experiences of physically active adults ('Actives') during the COVID-19 pandemic, including their PA levels, barriers and facilitators to/for PA, the strategies they deployed to keep active and their experiences of the messaging of Government health and PA guidelines. Following recruitment, thirteen in depth semi-structured interviews were undertaken with adult men and women who reported meeting the UK Chief Medical Officer's PA guidelines before the COVID-19 pandemic commenced. Braun and Clarke's thematic analysis identified five key themes and related sub-themes: (I) PA participation; (II) barriers to PA participation, including overcrowding of the PA space, conflict between different groups and negative mental health; (III) facilitators for PA, including place/residence, rural location, social support and good mental wellbeing; (IV) strategies to keep active, including improvisation, substitution of PA mode, scheduling PA, social support and goal setting; (V) guidance and messaging on the health guidelines, including PA promotion for strength and balance, mental health and where to receive information on PA. This study provides valuable insights for PA promotion for Actives at an unprecedented time.
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http://dx.doi.org/10.3390/bs15050598 | DOI Listing |
JPEN J Parenter Enteral Nutr
September 2025
Center for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, Kumamoto, Japan.
Background: Limited evidence exists regarding the cognitive and physical improvement effects of medium-chain triglyceride (MCT) intake in patients with stroke. This study aimed to investigate the association between MCT-enhanced rice consumption and enhancements in outcomes, including cognitive level, in patients following stroke.
Methods: We performed a retrospective cohort study on adults admitted to a rehabilitation center with cognitive decline following acute stroke.
Lab Anim Res
September 2025
Department of Pathology, Faculty of Medicine, Kindai University, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan.
Background: Stroke-prone spontaneously hypertensive rats (SHRSP) exhibit slow-twitch muscle-specific hypotrophy compared with normotensive Wistar-Kyoto rats (WKY). Because slow-twitch muscles are prone to disuse atrophy, SHRSP may experience both disuse atrophy and impaired recovery from it. This study investigated the response of SHRSP to disuse atrophy and subsequent recovery, using WKY as a control.
View Article and Find Full Text PDFObes Surg
September 2025
Department of Experimental Vascular Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Background: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are common bariatric procedures that lead to substantial and sustained weight loss. Although both procedures induce hormonal and physiological effects, RYGB includes both a restrictive and malabsorptive component due to anatomical rerouting, whereas SG is considered primarily restrictive. This study aimed to quantify differences in energy and fat absorption between both procedures using near-infrared spectroscopy (NIRS).
View Article and Find Full Text PDFJ Neural Transm (Vienna)
September 2025
Department of Clinical and Health Psychology, University of Vienna, Liebiggasse 5, Vienna, 1010, Austria.
Tiredness may be associated with increased or decreased sexual experience and behavior while fatigue seems to have a predominantly negative effect, although evidence is scarce. This ecological momentary assessment study is the first to examine associations between tiredness or fatigue and concurrent / subsequent sexual desire or sexual arousal and previous / subsequent sexual activity in daily life, including event-based measurements and considering gender differences. Healthy heterosexual individuals (n = 63), aged between 19 and 32 years and in a relationship, indicated their tiredness, general fatigue, physical fatigue, sexual desire, and sexual arousal on an iPod seven times daily over 14 days, and any event-based occurrences of sexual activity.
View Article and Find Full Text PDFNat Nanotechnol
September 2025
John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
Adoptive T-cell therapies, and particularly CAR T cells and tumour-infiltrating lymphocytes, have transformed cancer treatment by selectively targeting malignant cells. Despite their clinical success, these therapies face substantial challenges, including costly manufacturing processes and tumour-imposed barriers that limit efficacy. Advances in understanding the nanoscale mechanisms governing T-cell activation and the role of the tumour microenvironment in restricting T-cell responses have driven the development of nanotechnology-based strategies that integrate key chemical and physical cues.
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