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This project examined the Incidental Learning (IL) procedure from the Symbol-Digit Modalities Test (SDMT) as both a screening tool and as a measure of memory. Participants included undergraduate college students and stroke- and dementia-free older adult volunteers with and without hypertension or chronic kidney disease. In each sample, IL scores were correlated with performances from a variety of cognitive tasks. Results indicated that IL scores were more strongly associated with tests of memory than other cognitive abilities. As a screening instrument for older adults, scores of four or more recalled symbol-digit pairings strongly indicated a lack of difficulties on other tests of memory, whereas scores of three or fewer suggested a need for further assessment, though not necessarily impairment. A novel recognition (IL-r) procedure was introduced to older participants without kidney disease, and results indicated that IL-r uniquely predicted both delayed verbal and visual memory beyond standard IL. Our findings suggest that IL can be regarded as an efficient supplemental or screening test of memory that offers a complementary methodology to a comprehensive assessment of memory.
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http://dx.doi.org/10.1080/23279095.2025.2509088 | DOI Listing |
Arq Gastroenterol
September 2025
State University of Campinas, Faculty of Medical Sciences, Department of Surgery, Digestive Diseases Surgical Unit - Campinas (SP), Brazil.
Background: Gastroesophageal reflux disease has a prevalence of 12% in the Brazilian population. Its treatment includes hygienic-dietary changes, use of medications and, in selected cases, surgery with laparos-copic hiatoplasty and Nissen total fundoplication. However, this last treatment modality presents risks of postoperative dysphagia.
View Article and Find Full Text PDFBioinformatics
September 2025
Computational Health Center, Helmholtz Center Munich, Neuherberg, 85764, Germany.
Motivation: Recent pandemics have revealed significant gaps in our understanding of viral pathogenesis, exposing an urgent need for methods to identify and prioritize key host proteins (host factors) as potential targets for antiviral treatments. De novo generation of experimental datasets is limited by their heterogeneity, and for looming future pandemics, may not be feasible due to limitations of experimental approaches.
Results: Here we present TransFactor, a computational framework for predicting and prioritizing candidate host factors using only protein sequence data.
J Neurooncol
September 2025
Department of Radiotherapy and Radiation Oncology, Philipps- Universität Marburg, Marburg, Germany.
Background: Pituitary adenomas are relatively common benign intracranial tumors that may cause significant hormonal imbalances and visual impairments. Radiotherapy (RT) remains an important treatment option, particularly for patients with residual tumor after surgery, recurrent disease, or ongoing hormonal hypersecretion. This study summarizes long-term clinical outcomes and radiation-associated toxicities in patients with pituitary adenomas treated with contemporary radiotherapy techniques at a single institution.
View Article and Find Full Text PDFSupport Care Cancer
September 2025
Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Purpose: To compare the efficacy of intraoral (IOPBM) and extraoral photobiomodulation (EOPBM) protocols for the prevention and treatment of oral mucositis (OM) in patients with oral or oropharyngeal squamous cell carcinoma (SCC) to submitted radiotherapy (RT).
Methods: This randomized, blinded, multicenter clinical trial enrolled 58 patients with oral or oropharyngeal SCC, who were allocated into two groups matched by treatment type, clinical stage, and RT modality. Group I (IOPBM) received intraoral photobiomodulation (PBM) with a continuous InGaAlP diode laser (660 nm, 100 mW, 0.
AJR Am J Roentgenol
September 2025
Department of Radiology, Stanford University, Stanford, CA, USA.
The increasing complexity and volume of radiology reports present challenges for timely critical findings communication. To evaluate the performance of two out-of-the-box LLMs in detecting and classifying critical findings in radiology reports using various prompt strategies. The analysis included 252 radiology reports of varying modalities and anatomic regions extracted from the MIMIC-III database, divided into a prompt engineering tuning set of 50 reports, a holdout test set of 125 reports, and a pool of 77 remaining reports used as examples for few-shot prompting.
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