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This study identifies the outcome domains used in recently published studies on the treatment of hand flexor tendon injuries in adults, in order to inform the development of a core outcome set (COS). Seven databases were searched from January 2013 to March 2023 for randomized and quasi-randomized studies, trial registrations, large observational studies, database studies and systematic reviews. From the 91 eligible original studies/trial registrations, the primary outcome was appropriately identified in only 52% (13/25) of randomized and quasi-randomized controlled trials. We identified 419 author-defined outcomes, further categorized into 147 distinct outcomes and mapped into 72 outcome domains according to the World Health Organization International Classification of Functioning, Disability and Health framework. The large heterogeneity in the outcome domains being assessed/measured across studies highlights the need for a consistent COS to be measured in future clinical research on hand flexor tendon injuries.
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http://dx.doi.org/10.1177/17531934251342732 | DOI Listing |
Neural Regen Res
September 2025
Clinical Laboratory for Bionic Extremity Reconstruction, Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Vienna, Austria.
Stroke and traumatic brain injury lead to upper motor neuron syndrome, which is characterized by muscle spasticity or paresis of varying severity depending on the lesion's location and extent. Current treatments are mostly symptomatic with limited efficacy and significant side effects. Nerve transfer techniques, such as the contralateral L4 ventral root transfer in animal models and C7 root transfer in both animal and clinical studies, have been shown to reduce spasticity and improve function in upper motor neuron syndrome; however, they lack selectivity.
View Article and Find Full Text PDFPain Med Case Rep
August 2025
Hacettepe University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Ankara, Turkey.
Background: Although cases of tenosynovitis associated with foreign bodies are documented in the literature, there is no reported instance of the treatment of foreign body-associated tenosynovitis with ultrasound (US)-guided steroid injection. The use of corticosteroid injection under US guidance for flexor tenosynovitis associated with foreign bodies is a noteworthy subject.
Case Report: In this case report, we present the contribution of US-guided targeted steroid injection to the treatment of flexor tenosynovitis of the third finger of the left hand associated with a foreign body.
J Clin Neurophysiol
September 2025
Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Purpose: This study aimed to evaluate the intraoperative localization and prognostic utility of electrophysiologic monitoring for upper limb and hand muscle groups during contralateral C7 nerve transfer surgery.
Methods: In this retrospective, dual-center study, patients with spastic hemiparesis of a single upper limb who underwent contralateral C7 nerve transfer between July 2022 and November 2023 at the First Affiliated Hospital of Soochow University and Nanjing Drum Tower Hospital were included. Sensory, motor, and muscle tone changes were assessed using free electromyography, compound muscle action potentials, somatosensory evoked potentials, and transcranial electrical stimulation motor evoked potentials.
Exp Brain Res
September 2025
Neuromotor Adaptation Laboratory, Faculty of Science, Medicine, and Health, School of Medical, Indigenous, and Health Sciences, University of Wollongong, Northfields Avenue, Wollongong, 2522, NSW, Australia.
Hand control for dexterous and strength-based tasks involves several levels of the neuromuscular system which interact to produce force. We investigated hand force, motor unit (MU) control, and intermuscular coherence in specialist-trained groups to identify how training may affect neuromuscular force control and motor neuron activity. Equal groups of ten strength-trained (rock climbers) and dexterity-trained (musicians) individuals participated.
View Article and Find Full Text PDFJ Diagn Med Sonogr
April 2025
Chan Division of Occupational Science and Occupational Therapy, University of Southern California.
Objective: Currently, no standardized sonography protocol for evaluating the distal flexor tendons in the hand exists. The aims of this research were to 1) establish an image acquisition protocol to standardize assessment and 2) describe typical variations in the morphology of flexor tendons in healthy individuals.
Materials And Methods: A sonography protocol was developed, refined, and deployed in a cohort of healthy volunteers to collect images and cine clips of flexor tendons beginning at the mid-palm through insertion at the distal phalanx.