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PM, particulate matter with an aerodynamic diameter smaller than 1.0 µm, can adversely affect human health. However, fewer stations are capable of measuring PM concentrations than PM and PM concentrations in real time (i.e., only 9 locations for PM vs. 623 locations for PM or PM) in South Korea, making it impossible to conduct a nationwide health risk analysis of PM. Thus, this study aimed to develop a PM prediction model using a random forest algorithm based on PM data from the nine measurement stations and various environmental input factors. Cross validation, in which the model was trained in eight stations and tested in the remaining station, achieved an average R of 0.913. The high R value achieved under mutually exclusive training and test locations in the cross validation can be ascribed to the fact that all the locations had similar relationships between PM and the input factors, which were captured by our model. Moreover, results of feature importance analysis showed that PM and PM concentrations were the two most important input features in predicting PM concentration. Finally, the model was used to estimate the PM concentrations in 623 locations, where input factors such as PM and PM can be obtained. Based on the augmented profile, we identified Seoul and Ansan to be PM concentration hotspots. These regions are large cities or the center of anthropogenic and industrial activities. The proposed model and the augmented PM profiles can be used for large epidemiological studies to understand the health impacts of PM.
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http://dx.doi.org/10.1016/j.jes.2024.06.029 | DOI Listing |
JDS Commun
September 2025
Department of Animal and Veterinary Sciences, the University of Vermont, Burlington, VT 05405.
Optimizing calf feeding strategies is critical for improving performance, health, and weaning transitions of preweaning animals. Despite the updated National Academies of Sciences, Engineering, and Medicine (NASEM, 2021) , decision support tools integrating these equations for simulating optimized calf feeding strategies remain limited. To address this gap, we developed and tested the CalfSim, a free, user-friendly decision support tool designed to simulate and optimize feeding plans for dairy calves.
View Article and Find Full Text PDFHealth Econ Policy Law
September 2025
Department of Health Policy, London School of Economics and Political Science, London, UK.
While a substantial amount of evidence exists on factors associated with positive health technology assessment (HTA) outcomes, the evidence on the same regarding rejections is scarce. Using a proprietary dataset of HTA outcomes in seven Organisation for Economic Co-operation and Development (OECD) countries, we empirically examine the factors associated with HTA rejections and study the magnitude of inter-agency differences in technology appraisals. Data were extracted from HTA reports between 2009 and 2020.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
September 2025
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, USA.
Maintenance of organismal function requires tightly regulated biomolecular communication. However, with aging, communication deteriorates, thereby disrupting effective information flow. Using information theory applied to skeletal muscle single cell RNA-seq data from young, middle-aged, and aged animals, we quantified the loss of communication efficiency over time.
View Article and Find Full Text PDFBackground: Emergency department (ED) overcrowding has become a widespread global problem, with multi-factorial causes spanning input, throughput, and output domains. In Taiwan, the unique context of universal health coverage and a severe nursing shortage further complicates the situation. The Lunar New Year holiday period is associated with increased ED demand, yet the extent, causes, and responses to post-holiday overcrowding remain unclear.
View Article and Find Full Text PDFFront Plant Sci
August 2025
Institute of Biotechnology, Inner Mongolia Tongliao Agricultural and Animal Husbandry Academy, Tongliao, China.
Introduction: Straw return combined with rational nitrogen (N) fertilization plays a critical role in coordinating the transformation of soil organic carbon and nitrogen availability, thereby improving nitrogen use efficiency (NUE), crop yield, and soil fertility. However, the dynamics of soil carbon and nitrogen fractions under straw return with varying N inputs, and their specific contributions to NUE and yield, remain unclear.
Methods: A three-year split-plot field experiment was conducted in the Tumochuan Plain Irrigation District.