Molecular chemosensors for hazardous anions (AcO, CN and F): progress in fluorescent and colorimetric detection strategies.

Spectrochim Acta A Mol Biomol Spectrosc

Department of Chemistry, Rajalakshmi Engineering College, Chennai 602105, India. Electronic address:

Published: November 2025


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Article Abstract

This review provides a comprehensive analysis of recent advancements in the development of molecular chemosensors for the detection of hazardous anions such as acetate (AcO), cyanide (CN), and fluoride (F), with a particular focus on fluorescent and colorimetric detection strategies. It examines the fundamental principles of molecular recognition and sensor design, highlighting how specific binding interactions and structural tuning contribute to enhanced selectivity and sensitivity. The review discusses innovative synthetic approaches and the integration of various signaling mechanisms that enable rapid and reliable detection in complex matrices, addressing both the challenges of interference and the need for real-time monitoring in environmental, industrial, and biomedical applications.

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http://dx.doi.org/10.1016/j.saa.2025.126414DOI Listing

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