Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Introduction: Digital point-of-care information resources are frequently used by clinicians to answer clinical questions. An evidence-based disease management database (DynaMed) was merged with a pharmaceutical knowledge base (Micromedex). We evaluated the ability of the combined solution, DynaMedex, to answer clinical questions.

Methods: Real-world questions were used for testing and were categorized by information type and specialty area. Two pharmacists independently performed 600 searches for 300 questions, using keyword search and Watson Assistant (WA). Search results were evaluated based on whether information was found (yes, no), relevance to the question (relevant, not relevant), difficulty in finding the answer (easy, medium, hard), and quality of the evidence (good, fair, poor).

Results: An answer was found 86.3% of the time using keyword search and 81.0% of the time using WA. In keyword searches, 86.0% of answers were considered relevant and 74.5% in WA. Most answers were easy to find (78.7% in keyword search, 94.4% in WA). The quality of evidence for answers was good, fair, or poor in 62.7%, 36.4%, and 0.9% for keyword search and 50.3%, 47.8%, and 1.9% for WA.

Conclusion: Pharmacists found answers to most clinical questions easily with good quality, evidence-based information and a high agreement rate. This resource could be further improved by recognizing different search terms, standardizing the location of drug and disease information in appropriate sections, providing citations, if available, with the highest quality evidence, and including access to content types that haven't been incorporated.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijmedinf.2025.105965DOI Listing

Publication Analysis

Top Keywords

keyword search
16
quality evidence
12
real-world questions
8
answer clinical
8
clinical questions
8
good fair
8
time keyword
8
search
6
questions
5
keyword
5

Similar Publications

Introduction: It is well known that Obstructive Sleep Apnea (OSA) is a complex disease characterized by an Upper Airway (UA) collapse during sleep, with potential consequences on ENT districts. Recent evidence suggests a possible association with Eustachian Tube Dysfunction (ETD). However, the potential effects of both surgical and non-surgical therapeutic strategies on ET function remain poorly explored in the current literature.

View Article and Find Full Text PDF

Objective: The objective of this study was to systematically explore how culture has been conceptualized, investigated, and measured within general surgery residency training programs.

Summary Background Data: Research on the culture of general surgery residency training programs has primarily focused on examining individual parameters, such as mistreatment and burnout, rather than comprehensively analyzing the overall culture, climate, or learning environment.

Methods: Five databases (PubMed, Embase, Cochrane, CINAHL, APA PsycInfo) were searched.

View Article and Find Full Text PDF

Background: Schizotypy (ST) and psychotic-like experiences and negative symptoms (PENS) are commonly used phenotypes in high-risk and early intervention research for schizophrenia and other non-affective psychoses. However, the origin of these phenotypes in the general population is poorly understood and their association with the genetic predisposition to psychoses has not yet been proven.

Aim: The aim of this study is to answer the question of whether data on the relations of ST and PENS with polygenic risk scores for schizophrenia (SZ-PRS) support the hypothesis that these phenotypes are subclinical manifestations of genetic liability for schizophrenia.

View Article and Find Full Text PDF

Background: Addictive disorders remain a global problem, affecting health, society and the economy. The etiopathogenesis of addictions, which have a multifactorial nature, is poorly understood, making it difficult to develop personalized treatment approaches. Of particular interest is the gene, which regulates serotonergic transmission.

View Article and Find Full Text PDF

Red yeast rice (RYR) is an Asian indigenous medicine that ferments grains using the Monascus fungi, specifically . Monacolins, pigments, phenols, sterols, and benzopyrans, such as the mycotoxin citrinin, were proven to be present in RYR, contributing to its numerous effects. This study aims to provide a thorough overview of the in vitro and in vivo pharmacological activities of red yeast rice, its studies in humans, and a summary of recent case reports.

View Article and Find Full Text PDF