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Coronary obstruction is a rare but serious complication during transcatheter aortic valve implantation (TAVI), particularly in valve-in-valve procedures, which is associated with high mortality. This review explores various leaflet modification techniques designed to mitigate this risk. Among the most studied methods is Bioprosthetic or native Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction (BASILICA), which uses transcatheter electrosurgery to lacerate the aortic valve leaflet and maintain coronary perfusion. Other promising techniques include ShortCut, a mechanical leaflet splitting device, and Undermining Iatrogenic Coronary Obstruction with Radiofrequency Needle (UNICORN), which utilises radiofrequency energy to achieve leaflet laceration. These approaches differ in their procedural complexity, equipment requirements, and clinical outcomes. Each technique's efficacy in preventing coronary obstruction is discussed, alongside the potential complications and the procedural challenges encountered in both native aortic valve and valve-in-valve settings. This review also highlights the importance of careful patient selection, advanced imaging techniques, and the need for further research to optimise these strategies.
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http://dx.doi.org/10.4244/EIJ-D-24-00972 | DOI Listing |
Eur J Vasc Endovasc Surg
September 2025
Department of Vascular Surgery, University Hospital, LMU Munich, Munich, Germany.
Objective: This study aimed to evaluate treatment indications, compare therapeutic approaches, and assess outcomes in patients with infrarenal penetrating aortic ulcers (iPAUs).
Methods: This was a retrospective, multicentre, observational study of patients with iPAUs treated between January 2018 and December 2022 across 12 European centres. Treatment strategies included open surgical repair (OSR) and endovascular techniques, including balloon expandable stent grafts (BESGs), covered endovascular reconstruction of the aortic bifurcation (CERAB), and endovascular aortic repair (EVAR) using bifurcated or tube grafts.
Int J Cardiol
September 2025
Department of Radiology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250021, China; Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China. Electronic address:
Objective: This study aimed to enhance major adverse cardiovascular events (MACEs) prediction by pericoronary adipose tissue attenuation (PCATa) in non-obstructive coronary artery disease (CAD) patients when combined with lipoprotein (a) (Lp(a)).
Methods: A total of 1052 patients with non-obstructive CAD were included. Detailed clinical data and CCTA features were analyzed.
Eur Geriatr Med
September 2025
School of Public Health Sciences, University of Waterloo, Waterloo, Canada.
Purpose: Sleep disturbance is prevalent in long-term care facilities (LTCFs), yet there is limited understanding of individual factors predicting changes in sleep within these populations. Our objective was to determine predictors of sleep disturbance in LTCFs and investigate variation in prevalence across facilities in two Canadian provinces-New Brunswick and Saskatchewan.
Method: This retrospective longitudinal cohort study used interRAI comprehensive health assessment data from 2016 to 2021, encompassing 21,394 older adults aged ≥ 65 years across 228 LTCFs.
AJR Am J Roentgenol
September 2025
Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Patients with inflammation-associated coronary artery disease (CAD) may exhibit rapid progression and require regular coronary imaging. To evaluate the diagnostic performance of spectral photon-counting detector (PCD) coronary CTA with reduced radiation and contrast media doses for detecting coronary stenosis and in-stent restenosis in patients with inflammation-associated CAD. This prospective study enrolled patients with inflammation-associated CAD from January 2023 to March 2024.
View Article and Find Full Text PDFERJ Open Res
September 2025
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Background: Measurement of total lung capacity (TLC) requires large and expensive equipment. We aimed to investigate whether spirometric restriction and low alveolar volume measured by single breath gas transfer ( ) can be used to identify those with a low TLC.
Methods: We retrospectively analysed data from adults referred to Cambridge University Hospitals between January 2016 and December 2023.