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Purpose: To identify the determinants to successfully implement a community-based intervention to increase eye care utilization in individuals at high-risk for eye diseases.
Design: Qualitative study with semi-structured interviews.
Methods: Semi-structured qualitative interviews were conducted with community members in Detroit, Michigan at a trusted community site. Participants were Black Americans at least 40 years of age. A codebook of themes was developed through an iterative process and analyzed using Dedoose.
Results: Narrative themes emerged under 2 overarching categories: barriers and facilitators. The number of themes identified were 15 and 14 for barriers and facilitators, respectively. All perceived barriers and facilitators fell into one or more domains of the social determinants of health model.
Conclusions: Identifying facilitators and eliminating barriers to eye care in Black and low-income communities is essential to successful implementation of interventions to increase eye care utilization. Understanding how these determinants align with social determinants of health may be helpful in designing community-based interventions. Community-based participatory research methods are critical to achieving equity in eye care.
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http://dx.doi.org/10.1016/j.ajo.2025.05.006 | DOI Listing |
Neurol Neuroimmunol Neuroinflamm
November 2025
Departments of Neurology and Ophthalmology, NYU Grossman School of Medicine, NY; and.
Background And Objectives: While reductions in optical coherence tomography (OCT) pRNFL and ganglion cell-inner plexiform layer thicknesses have been shown to be associated with brain atrophy in adult-onset MS (AOMS) cohorts, the relationship between OCT and brain MRI measures is less established in pediatric-onset MS (POMS). Our aim was to examine the associations of OCT measures with volumetric MRI in a cohort of patients with POMS to determine whether OCT measures reflect CNS neurodegeneration in this patient population, as is seen in AOMS cohorts.
Methods: This was a cross-sectional study with retrospective ascertainment of patients with POMS evaluated at a single center with expertise in POMS and neuro-ophthalmology.
Diabetes Care
September 2025
Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA.
Objective: This study aimed to evaluate the diabetic eye disease screening continuum at two academic centers and identify its barriers.
Research Design And Methods: We analyzed health records from the University of California, San Francisco and University of California, Irvine to identify primary care patients needing diabetic eye screening. We tracked referrals, screenings, diagnoses, and treatments to evaluate predictors and the impact of an automated referral system.
Retina
September 2025
School of Mathematical and Computational Sciences, University of Prince Edward Island, Charlottetown, Canada.
Purpose: Systemically administered anti-cancer VEGF inhibiting therapies can cause severe kidney injury. Intravitreal aflibercept has a greater impact on renal VEGF levels than ranibizumab. We compared the risk of kidney injury among patients receiving intravitreal aflibercept vs.
View Article and Find Full Text PDFTissue Eng Regen Med
September 2025
Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #505 BanPo-Dong, SeoCho-Gu, Seoul, 06591, Republic of Korea.
Background: Sjögren's syndrome (SS) is a chronic autoimmune disease delineated by excessive lymphocyte infiltration to the lacrimal or salivary glands, leading to dry eye and dry mouth. Exosomes secreted from mesenchymal stem cells (MSC) are known to have anti-inflammatory and tissue regeneration abilities. This study endeavored to demonstrate the effect of MSC-derived exosomes on the clinical parameter of dry eyes and associated pathology in SS mouse model.
View Article and Find Full Text PDFClin Transl Oncol
September 2025
Ophthalmology Unit, Cannizzaro Hospital, 95126, Catania, Italy.
Antibody-drug conjugates (ADCs) represent a promising therapeutic approach in gynecologic cancers, particularly ovarian and cervical malignancies. Agents such as mirvetuximab soravtansine, and tisotumab vedotin, targeting folate receptor alpha and tissue factor, respectively, reported clinical efficacy in patients with limited options. However, their use is associated with ocular toxicities, including keratopathy, blurred vision, and dry eye, which may impact adherence and quality of life.
View Article and Find Full Text PDF