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Artificial intelligence and machine learning are rapidly transforming medicine, healthcare, and surgery. Machine learning is a valuable tool for surgeons and researchers in pediatric cardiovascular and thoracic surgery, with innovative applications constantly evolving and expanding. Utilizing machine learning in addition to traditional statistical methods can gain insights into the data and develop more powerful prediction models for improving surgical management and patient outcomes. We provide an accessible introduction to machine learning for surgeons to become familiar with its key essential concepts and architecture, along with a five-step strategy for performing machine learning analyses. With careful study planning using high-quality data, active collaboration between surgeons, researchers, statisticians, and data scientists, and real-world implementation of machine learning algorithms in the clinical setting, machine learning can be a strategic tool for gaining insights into the data in order to improve surgical decision-making, patient risk management, and surgical outcomes.
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http://dx.doi.org/10.1177/21501351251335643 | DOI Listing |
J Clin Invest
September 2025
The University of Texas at Austin, Austin, United States of America.
Background: Following SARS-CoV-2 infection, ~10-35% of COVID-19 patients experience long COVID (LC), in which debilitating symptoms persist for at least three months. Elucidating biologic underpinnings of LC could identify therapeutic opportunities.
Methods: We utilized machine learning methods on biologic analytes provided over 12-months after hospital discharge from >500 COVID-19 patients in the IMPACC cohort to identify a multi-omics "recovery factor", trained on patient-reported physical function survey scores.
Proc Natl Acad Sci U S A
September 2025
Max Planck Institute for Solar System Research, Göttingen 37077, Germany.
Turbulent convection governs heat transport in both natural and industrial settings, yet optimizing it under extreme conditions remains a significant challenge. Traditional control strategies, such as predefined temperature modulation, struggle to achieve substantial enhancement. Here, we introduce a deep reinforcement learning (DRL) framework that autonomously discovers optimal control policies to maximize heat transfer in turbulent Rayleigh-Bénard convection.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
September 2025
Division of Plastic and Reconstructive Surgery, Neonatal and Pediatric Craniofacial Airway Orthodontics, Department of Surgery, Stanford University School of Medicine, 770 Welch Road, Palo Alto, CA, 94394, USA.
Background: Alveolar molding plate treatment (AMPT) plays a critical role in preparing neonates with cleft lip and palate (CLP) for the first reconstruction surgery (cleft lip repair). However, determining the number of adjustments to AMPT in near-normalizing cleft deformity prior to surgery is a challenging task, often affecting the treatment duration. This study explores the use of machine learning in predicting treatment duration based on three-dimensional (3D) assessments of the pre-treatment maxillary cleft deformity as part of individualized treatment planning.
View Article and Find Full Text PDFHepatol Int
September 2025
Department of Biomedical Informatics and Data Science, Yale School of Medicine, PO Box 208009, New Haven, CT, 06520-8009, USA.
Int J Cardiovasc Imaging
September 2025
Klinikum Fürth, Friedrich-Alexander-University Erlangen- Nürnberg, Fürth, Germany.
Myocarditis is an inflammation of heart tissue. Cardiovascular magnetic resonance imaging (CMR) has emerged as an important non-invasive imaging tool for diagnosing myocarditis, however, interpretation remains a challenge for novice physicians. Advancements in machine learning (ML) models have further improved diagnostic accuracy, demonstrating good performance.
View Article and Find Full Text PDF