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This study presents an innovative ultrasound-guided technique for central venous access in patients with venous occlusion, particularly in those requiring long-term parenteral nutrition (TPN). Conventional access points often become occluded, necessitating alternative methods for approaching the central vein. A retrospective review of three patients with venous occlusion due to prolonged TPN use was conducted at our institution. The procedure involved ultrasound-guided puncture of atypical vessels, such as the internal mammary, anterior jugular, or innominate veins, using the Seldinger or introducer technique depending on vessel size. All catheters were successfully placed with minimal complications, allowing for continued TPN. The study concluded that ultrasound-guided access to atypical vessels offers a safer and less invasive alternative to central venous access in complex cases, particularly in adolescent and young adult patients.
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http://dx.doi.org/10.1007/s00595-025-03056-4 | DOI Listing |
Arterial thrombosis is a multifaceted process characterized by platelet aggregation and fibrin deposition, leading to the occlusion of blood vessels. It plays a central role in cardiovascular conditions such as myocardial infarction and ischemic stroke. Gaining insight into the mechanisms underlying arterial thrombosis is essential for developing effective treatments aimed at preventing thrombotic events and reducing associated health burdens.
View Article and Find Full Text PDFKhirurgiia (Mosk)
September 2025
Mandryka Central Military Clinical Hospital, Moscow, Russia.
Widespread fragmentation shells in combat operations with frequent multiple damage to organs and systems force to use all available diagnostic methods for treating severe injuries including lesion of great vessels of extremities. One of the consequences of these lesions is arteriovenous fistula (AVF). The last one may be asymptomatic at first.
View Article and Find Full Text PDFN Engl J Med
September 2025
Division of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea.
Background: Previous results from this phase 3 trial showed that progression-free survival among participants with previously untreated (epidermal growth factor receptor)-mutated advanced non-small-cell lung cancer (NSCLC) was significantly improved with amivantamab-lazertinib as compared with osimertinib. Results of the protocol-specified final overall survival analysis in this trial have not been reported.
Methods: We randomly assigned, in a 2:2:1 ratio, participants with previously untreated -mutated (exon 19 deletion or L858R substitution), locally advanced or metastatic NSCLC to receive amivantamab-lazertinib, osimertinib, or lazertinib.
Acta Paediatr
September 2025
Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Department of Pediatrics, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria.
Aim: Successful procedural performance in a Neonatal Intensive Care Unit (NICU) depends on skill performance and preparation. Checklists are beneficial, and video reviewing enhances adherence to guidelines. This study assessed whether video recordings can be used to assess checklist deviations, the extent to which proceduralists (doctors from 1 to ≥ 6 years of experience) deviate from checklists, and whether video recordings can help to improve existing and create new checklists.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Nephrology and Blood Purification, Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
Rationale: This case report aims to highlight a rare but life-threatening complication of femoral venous catheterization and to describe a novel endovascular technique for its management. Non-tunneled femoral catheters provide rapid vascular access for emergency dialysis (e.g.
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