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Objective: While the impact of annual caseload on short term outcomes after abdominal aortic aneurysm (AAA) repair remains under debate, current data from the most decentralised healthcare system in Europe may offer valuable insights into an area that has changed considerably due to the widespread use of endovascular aortic aneurysm repair (EVAR).
Methods: This was a retrospective observational study of multicentre quality registry data from Germany on EVAR for intact and ruptured AAA between January 2017 and December 2023. The impact of annual caseload and risk factors on in hospital death, complication rates, and failure to rescue after intact AAA repair was determined using multivariable logistic regression models.
Results: A total of 19 641 individuals (n = 2 576 females [13.1%]; median age 74 years, interquartile range [IQR] 68, 80) who underwent EVAR for intact (n = 18 763) or ruptured (n = 878) AAA were included from 194 centres. Among these, 44.3% of males were selected for treatment with a maximum diameter < 55 mm (31.8% of females < 50 mm). After a median length of hospital stay of six days (IQR 5, 8) and 10 days (IQR 6, 17) for intact and ruptured cases, 1.0% and 19.7% died, respectively. The rate of any post-interventional complication was 8.2% and 31.4%, respectively. An endoleak was apparent on the completion angiogram in 17.6% of intact cases (14.5% type II) and 18.2% of ruptured cases (11.0% type II). The median annual EVAR caseload per centre was 34.7 (IQR 22.1, 58.4), and 25.1% of patients were treated at centres above the 75th percentile. An American Society of Anesthesiologists (ASA) score ≥ 4, juxtarenal aneurysm extent, severe heart failure, female sex, larger aneurysm diameter, older age, and history of cancer, chronic obstructive pulmonary disease, and stroke were associated with in hospital death after intact AAA repair, but annual caseload and severe chronic kidney failure were not. Sensitivity analyses including different outcomes were confirmative, except for a statistically significant impact of annual caseload on the composite endpoint of any post-interventional complication (p = .008).
Conclusion: This large registry analysis was unable to confirm an impact of caseload on short term results after EVAR for intact AAA. Future studies should address long term outcomes after EVAR as well as the underlying reasons for the considerably large proportion of small diameter AAA treatment.
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http://dx.doi.org/10.1016/j.ejvs.2025.05.012 | DOI Listing |
Circ J
September 2025
Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University.
Eur J Vasc Endovasc Surg
September 2025
School of Health and Medical Sciences, City St George's University of London, London, UK; St George's Vascular Institute, St George's Hospital, London, UK; Department of Surgery and Cancer, Imperial College London, London, UK. Electronic address:
Objective: Sex specific anatomical differences may contribute to observed disparities in outcomes and suitability for endovascular aneurysm repair (EVAR) between men and women with abdominal aortic aneurysms (AAAs). This study aimed to assess these differences using fully automated volume segmentation (FAVS) and explore implications for EVAR suitability.
Methods: This was a retrospective, multicentre cohort study of patients undergoing elective AAA repair between 2013 and 2023 in three UK tertiary centres.
Eur J Vasc Endovasc Surg
September 2025
Department of Surgery, Division of Vascular Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:
Objective: Despite the growing number of vascular interventions performed in elderly patients, the functional outcomes regarding frailty remain unclear. This study aimed to evaluate and compare the short term functional outcomes in pre-operative frail vs. non-frail patients following open vs.
View Article and Find Full Text PDFEur J Vasc Endovasc Surg
September 2025
Vascular Surgery, Aortic Center, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, INSERM UMR_S 999, Université Paris Saclay, Paris, France. Electronic address:
Objective: The aim of this study was to evaluate the association between operative time (OT) and post-operative outcomes in complex endovascular aortic repair and to explore contributing factors to OT.
Methods: This retrospective, observational cohort study analysing data from a single centre included patients undergoing fenestrated endovascular aortic repair (FEVAR), branched endovascular aortic repair (BEVAR), or arch branched endovascular aortic repair (aBEVAR) from February 2018 to December 2024. OT was defined as the interval from first arterial access to closure.
Biochem Biophys Res Commun
September 2025
Department of Vascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, 410011, China; Institute of Vascular Diseases, Central South University, Changsha, 410011, China. Electronic address:
Abdominal aortic aneurysm (AAA) is a potentially life-threatening vascular condition that currently lacks effective pharmacological treatment. The disease is strongly associated with chronic inflammation, where immune cells like macrophages play a crucial role. Efferocytosis, the process by which apoptotic cells are cleared, is involved in regulating inflammation.
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