Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Left atrial appendage closure (LAAC) has been reported to be a viable alternative to prevent thromboembolic events for atrial fibrillation (AF) patients. Interatrial communication closure, such as atrial septal defect (ASD) and patent foramen ovale (PFO) closure could significantly decrease the occurrence of stroke. For AF patients with interatrial communication, the success rate as well as the long-term outcomes of 'One stop' closure remain elusive.
Methods: Studies were systematically screened using online databases (including PubMed, Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure (CNKI) database, and WanFang database) from their establishment to 1st August 2024. We utilized a fixed-effect model to synthesize the success rate and the long-term outcomes. Subgroup analysis was performed to identify the potential confounders.
Results: A total of 7 studies comprising 156 patients were included. ASD/PFO closure combined with LAAC showed a high degree of feasibility, with a success rate of 1.00 (95% CI: 0.99, 1.00; < 0.001). Meanwhile, 'One stop' ASD/PFO closure combined with LAAC exhibited a high long-term safety and a low occurrence of complications. Moreover, subgroup analysis revealed that the bleeding event occurrence was relatively higher in the male proportion ≥50% subgroup and HAS-BLED score ≥3 subgroup, respectively.
Conclusions: ASD/PFO closure combined with LAAC has a satisfying performance on AF patients with interatrial communication.
The Prospero Registration: CRD42023462221, https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462221.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12059784 | PMC |
| http://dx.doi.org/10.31083/RCM26662 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Heart 3D: echocardiographic and anatomical features of the tricuspid valve in a heterogeneous population with severe regurgitation-implications for edge-to-edge procedure suitability.
Front Cardiovasc Med
August 2025
First Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Aim: To assess the incremental value of real-time three-dimensional (3D) transesophageal echocardiography (TEE) in visualizing tricuspid valve (TV) anatomy for procedural planning and guidance of transcatheter edge-to-edge repair (TEER) in cases of severe tricuspid regurgitation (TR).
Materials And Methods: An observational study was conducted on 54 patients with severe TR. The visualization of the TV leaflets during systole was graded semiquantitatively using predefined criteria: 0 points-no visible leaflet border or tissue; 1.
Bipolar radiofrequency ablation for refractory scar-related interatrial septal tachycardias: a multicenter study.
J Interv Card Electrophysiol
September 2025
Electrophysiology Section, Cardiovascular Division, Cleveland Clinic, Cleveland, OH, USA.
Background: Catheter ablation of scar-related interatrial septal atrial tachycardias (IAS-ATs) is challenging and can be refractory to conventional unipolar radiofrequency catheter ablation (RFCA).
Aim: This multicenter study investigated the safety and efficacy of bipolar radiofrequency catheter ablation (Bi-RFCA) in patients with IAS-AT refractory to conventional unipolar RFCA.
Methods: Consecutive patients with scar-related IAS-AT refractory to conventional unipolar RFA across three electrophysiological centers were included in the study.
Complicated Lipomatous Hypertrophy of the Interatrial Septum: Multimodality Imaging in Diagnosis and Management.
JACC Case Rep
September 2025
Division of Cardiovascular Imaging, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Background: Lipomatous hypertrophy of the interatrial septum (LHIS) is a benign cardiac lesion characterized by excessive fat accumulation in the interatrial septum, often sparing the fossa ovalis. Although typically asymptomatic, severe cases may lead to hemodynamic compromise.
Cases Summary: We report 2 cases of exuberant symptomatic LHIS requiring surgical intervention.
Interatrial block predicts left atrial appendage thrombus in nonvalvular atrial fibrillation.
J Electrocardiol
September 2025
Department of Cardiology, Ankara City Hospital, Health Sciences University, Ankara, Turkey.
Background: Interatrial block (IAB) is an electrocardiographic manifestation of atrial conduction delay and structural remodeling. While it has been linked to atrial fibrillation (AF) and thromboembolic events, its potential role in predicting left atrial appendage (LAA) thrombus formation remains underexplored. This study aimed to investigate the association between IAB and the presence of LAA thrombus in patients with nonvalvular AF (NVAF) or atrial flutter referred for rhythm control procedures.
View Article and Find Full Text PDFAtrial Mechanics in Heart Failure With Preserved Ejection Fraction: Effect of a No-Implant Interatrial Shunt.
Circ Heart Fail
September 2025
Duke University, Durham, NC (F.A., V.K., M.F.).
Background: The atria play an important role in the pathophysiology of heart failure with preserved ejection fraction. Decreased left atrial strain is associated with worse clinical outcomes. The impact of no-implant interatrial shunting on atrial structure and function has not been described.
View Article and Find Full Text PDF