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Objective: This randomised controlled trial evaluated the efficacy of the Tailored Injury Prevention in Adapted Sports (TIPAS) intervention on sports-related health problems in athletes participating in adaptive sports with physical impairments.
Methods: We randomly assigned 60 athletes participating in adaptive sports with physical impairments to an intervention group and 47 to a control group. The intervention group received direct, automated, predetermined preventive and management measures tailored to their weekly reported health problems, physical impairments and sports. The primary outcome was injury and illness prevalence over 40 weeks. Secondary outcomes were incidence, weekly cumulative severity score, weekly time loss, and total burden. A multinomial mixed methods analysis was performed to identify an intervention effect over time.
Results: The athletes (53 women, 54 men; age±45 years) reported 449 health problems (162 illnesses, 287 injuries) during the study period. The overall prevalence of health problems was 44% in the intervention group and 46% in the control group. Over time, no significant main intervention effect was found (illnesses OR: 1.02; 95% CI: 0.52 to 1.99; and injuries OR: 1.01; 95% CI: 0.55 to 1.86). However, a significant positive time×group interaction effect (p<0.001) indicated a reduction in injury prevalence in the intervention group over time, though not for illnesses. The rates versus severity analysis showed a significantly lower illness severity in the intervention group relative to the control group.
Conclusion: The TIPAS intervention provides a non-significant decrease in the overall prevalence of sport-related injuries and illnesses and may reduce the severity of sport-related illnesses throughout a Dutch sports season. This tailored online preventive strategy provides an accessible programme to consider in adapted sports suited to athletes' physical impairments, sports participation and current health status. : ICTRP register: NL-OMON24078.
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http://dx.doi.org/10.1136/bjsports-2024-108782 | DOI Listing |
Psychiatr Q
September 2025
Department of Psychological Counselling and Guidance, Yildiz Technical University, Istanbul, Türkiye.
Sleep is a significant factor influencing both physical and mental health. It supports thinking, emotional regulation, and vitality. However, insomnia is still a common problem, often linked to complex factors like psychological vulnerability and early life experiences.
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September 2025
Division of Infectious Diseases, Department of Medicine, University of Texas at Tyler School of Medicine, Tyler, Texas, USA.
Despite the long therapy duration, the treatment outcomes for lung disease (MAB-LD) are very poor. β-Lactams are among the recommended drugs for the treatment of MAB-LD; however, they are prone to hydrolysis by MAB β-lactamase enzymes. Therefore, β-lactamase inhibitors have been developed to overcome this problem.
View Article and Find Full Text PDFInt J Soc Psychiatry
September 2025
Department of Psychology at the Institute of Psychiatry, Psychology, and Neuroscience, King's College London, UK.
Background: Despite growing rates of common mental health disorders among country members of the Association of Southeast Asia Nations (ASEAN), there continue to be treatment gaps in these countries.
Aim: To systematically identify and synthesise barriers and facilitators to accessing formal psychological help for common mental health disorders in the existing literature.
Methods: APA PsycINFO, Web of Science, Scopus, and the Indonesian Portal Garuda were searched for studies reporting barriers or facilitators to individuals' engaging in formal psychological help-seeking for common mental health disorders in country members of ASEAN.
Phytochem Anal
September 2025
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Introduction: The drug "alkaloids of Sophora flavescens" (ASF) is an extract from the dried root of S. flavescens Ai. It has various pharmacological effects including anti-arrhythmia, anti-inflammatory, anti-allergic, anti-hepatitis, and antimicrobial.
View Article and Find Full Text PDFCochrane Database Syst Rev
September 2025
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Background: Radiotherapy is the mainstay of treatment for head and neck cancer (HNC) but may induce various side effects on surrounding normal tissues. To reach an optimal balance between tumour control and toxicity prevention, normal tissue complication probability (NTCP) models have been reported to predict the risk of radiation-induced side effects in patients with HNC. However, the quality of study design, conduct, and analysis (i.
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