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Objective: Despite increased access to online information, little is known about what factors patients consider when selecting a neurosurgeon for intracranial tumor resection. This study aims to identify patient priorities in neurosurgeon selection.
Methods: Patients who underwent intracranial tumor resection between January 1, 2023, and January 31, 2024, at a single institution were surveyed. They ranked 13 factors on a 5-point Likert scale. Survey data were analyzed alongside demographic and clinical information using ordinal logistic regression.
Results: Fifty patients (mean age 54.15 ± 13.82; 54 % female; 70 % white; 70 % privately insured) completed the survey. Surgeon caseload and procedure-specific experience (mean score 4.64 ± 0.72) were rated as most important, followed by hospital ranking (4.48 ± 0.68), years of experience (4.38 ± 0.75), and surgeon interpersonal skills (4.2 ± 1.14). Least important were social media presence, age, and word of mouth. Subgroup analysis revealed that non-Caucasian patients valued word of mouth more (OR: 1.65), while patients undergoing repeat surgery valued it less (OR: 0.33). Older patients, non-Caucasians, ethnic minorities, and married individuals placed less importance on medical school prestige.
Conclusion: Neurosurgical patients prioritize surgeon experience, hospital reputation, and interpersonal qualities. These insights can inform provider transparency, resource allocation, and outreach to underserved groups.
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http://dx.doi.org/10.1016/j.clineuro.2025.108932 | DOI Listing |
Neuropathology
October 2025
Pathology Department, Complejo Hospitalario Universitario de Toledo, Toledo, Spain.
Glioblastoma (GB), IDH-wildtype (IDH-wt), is the most prevalent primary malignant brain neoplasm in adults. Despite adjuvant therapy, the prognosis for these tumors remains dismal, with a median survival of around 15-18 months. Although rare, extracranial metastases from GB are reported with increasing frequency, likely due to advancements in follow-up, treatments, and improved patient survival.
View Article and Find Full Text PDFCurr Opin Virol
September 2025
Infection Biology, Global Center for Pathogen and Human Health Research, Cleveland Clinic, Cleveland, OH 44195, USA; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA. Electronic address:
Intracranial calcifications (ICCs) are a characteristic neuropathological feature of several congenital viral infections, including Zika virus (ZIKV), cytomegalovirus (CMV), and lymphocytic choriomeningitis virus (LCMV). These lesions are linked to severe neurodevelopmental outcomes, such as microcephaly, epilepsy, and cognitive deficits, yet the mechanisms underlying their formation and resolution remain unclear. ICCs are thought to arise from an imbalance in osteogenic and osteolytic signaling in the developing brain.
View Article and Find Full Text PDFPituitary
September 2025
Facoltà Di Medicina E Chirurgia, Università Cattolica del Sacro Cuore, Rome, Italy.
Introduction: Pituitary adenomas (PAs) are generally benign neoplasms, though in rare cases may exhibit aggressive behavior. In 2024, the PANOMEN-3 workshop released a new clinical-pathological classification. The objective of this study was to examine the potential of the PANOMEN-3 classification to predict prognosis of PAs and guide treatment in our single center cohort of patients with PAs.
View Article and Find Full Text PDFRedox Biol
August 2025
Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, No.119 South 4th Ring Road West, Beijing, China; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China; Beijing Engineering Research Center of Target
Glioma patients will inevitably develop resistance to temozolomide (TMZ) leading to tumor recurrence. By comparing genomic differences between primary and recurrent glioma patients, Thioredoxin reductase 1 (TrxR1) was identified as a crucial role in TMZ resistance. Glioma cells elevate the expression level of TXNRD1 to against TMZ-induced reactive oxygen species (ROS), thereby conferring TMZ resistance.
View Article and Find Full Text PDFActa Neurochir (Wien)
September 2025
Gui de Chauliac Hospital, Montpellier University Medical Center, Montpellier, France.
Background: Awake surgery is the reference for diffuse low-grade glioma resection, allowing maximal tumor removal while preserving neurocognitive functions. It is also applicable to other brain tumors. However, key technical elements must be followed to ensure optimal conditions for intraoperative cognitive testing and reliable functional mapping.
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