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Phytochemical investigation on roots extract of (L.) Holub led to the isolation of two novel ecdysteroids, 11-hydroxy-25-inokosterone (1) and 11-hydroxy-24, 25 -amarasterone A (2), along with 20 known constituents. The structures of novel compounds were confirmed by NMR and ECD spectroscopy. Compounds and exhibited anticomplementary activity with classical pathway, their CH values were 138.4 ± 0.07 µg·mL and 158.3 ± 0.09 µg·mL, respectively.
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http://dx.doi.org/10.1080/14786419.2025.2502855 | DOI Listing |
Fitoterapia
September 2025
Department of Natural Medicine, School of Pharmacy, Fudan University, Shanghai 201203, PR China; Institutes of Integrative Medicine, Fudan University, Shanghai 201203, PR China. Electronic address:
The pericarps of Trichosanthes kirilowii Maxim. (T. kirilowi) have been traditionally used in Chinese medicine for their heat-clearing properties.
View Article and Find Full Text PDFNat Prod Res
May 2025
Chemical R&D, School of Pharmaceutical Sciences, Hebei Key Laboratory of Innovative Drug Development and Evaluation, Hebei Medical University, Shijiazhuang, China.
Phytochemical investigation on roots extract of (L.) Holub led to the isolation of two novel ecdysteroids, 11-hydroxy-25-inokosterone (1) and 11-hydroxy-24, 25 -amarasterone A (2), along with 20 known constituents. The structures of novel compounds were confirmed by NMR and ECD spectroscopy.
View Article and Find Full Text PDFPhytochem Anal
July 2025
Department of Natural Medicine, School of Pharmacy, Fudan University, Shanghai, China.
Introduction: Myricariae Ramulus (MR) is a traditional anti-inflammatory Tibetan medicine derived from the branches and leafy twigs of various Myricaria plants, such as Myricaria wardii Marquand.
Objective: This study performed spectrum-effect analyses on 15 batches of MR, sourced from various origins and medicinal parts, to identify quality markers associated with its anti-inflammatory effects.
Materials And Methods: The anti-inflammatory effects of different extracts and fractions from M.
Front Pharmacol
August 2024
Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Harbin, China.
Int J Biol Macromol
September 2024
Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University College of Pharmacy, Yanji 133002, PR China. Electronic address:
The degradation of Belamcanda chinensis (L.) DC. polysaccharides was carried out by five concentrations of trifluoroacetic acid (TFA) (1-5 mol/L), and their physicochemical properties, degradation kinetics and anticomplementary activity were investigated.
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