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Aim Of The Study: Current guidelines advise rescuers to initiate cardiopulmonary resuscitation if a child is unresponsive, not breathing normally, and shows no signs of life. Manual pulse checks are considered unreliable and time-consuming. This systematic review evaluates the accuracy and duration of recommended pulse check methods during pediatric cardiac arrest and explores emerging diagnostic techniques.
Methods: For this systematic review (PROSPERO ID CRD42024549535) three databases (PubMed, Embase, and Cochrane) were searched for articles published on this topic. An initial search was conducted on April 24, 2024, with an updated search using the same search strategy on February 16, 2025. Two authors independently screened the articles. One author extracted the data while a second author double-checked it. Quality and certainty of the evidence were evaluated using the QUADAS-2 and GRADE tools evaluated the evidence's quality and certainty. Studies were included if they compared manual pulse checks against alternative pulse check sites or other methods in pediatric patients. The data is presented descriptively.
Results: A total of three studies were included. These studies involved 39 pediatric patients and a total of 376 pulse checks. Out of the 47 infants and children included, only 14 were in cardiac arrest. The remaining 33 patients were on mechanical circulatory support with either VA-ECMO or LVAD. In total, 183 nurses and 181 physicians performed 376 pulse or ultrasound checks. Due to their specialty, 122 nurses and 89 doctors were classified as experienced. Sensitivity and specificity of manual pulse check ranged from 76 to 100% and 64-79%, respectively. When experienced providers conducted pulse checks, sensitivity and specificity were higher (76-100% and 62-82%, respectively) compared to inexperienced providers (67-82% and 44-95%).The mean duration of pulse checks was 20 s, with an accuracy of 85%.
Conclusion: Despite high heterogeneity among included studies, manual pulse checks only achieved moderate accuracy with a prolonged duration. This suggests that manual pulse checks are unreliable in children for determination cardiac arrest state and need for ongoing CPR.
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http://dx.doi.org/10.1016/j.resplu.2025.100959 | DOI Listing |
J Evid Based Med
September 2025
Department of Cardiology, The Eighth Affiliated Hospital, Southern Medical University (the First People's Hospital of Shunde), Foshan, China.
Aim: The white-coat hypertension (WCH) detection by monitoring the out-of-office blood pressure (BP) consumes resources and time. This study aimed at developing the prediction model based on patients' characteristics obtained from clinical data.
Methods: Individuals who participated in two large hospitals health check-up examination were screened.
Cell Biol Int
September 2025
Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, India.
Diabetic cardiomyopathy (DCM) is a progressive heart disorder associated with diabetes mellitus, leading to structural and functional cardiac abnormalities. The mechanisms responsible include renin-angiotensin-aldosterone (RAAS) activation, inflammation, apoptosis, and metabolic disturbances. Despite well-established epidemiological links, treatments for DCM are elusive.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
September 2025
Objetive: This study aims to evaluate the QT adaptation time following gradual heart rate changes estimated from exercise stress test (EST) ECGs as a marker of sudden cardiac death (SCD) risk. The predicted risk value for any cardiovascular death (CVD) is also evaluated.
Methods: Three ECG-derived markers related to QT-RR adaptation time were estimated during the exercise phase of EST, $\check{\tau }_{e}$, during the recovery phase, $\check{\tau }_{r}$, and as the difference between them, $\Delta _{\check{\tau }}$.
Zh Nevrol Psikhiatr Im S S Korsakova
September 2025
Kazan State Medical University, Kazan, Russia.
Objective: To analyze the sex and age characteristics of modifiable risk factors for stroke in patients with type 2 diabetes mellitus (T2DM).
Material And Methods: The single-center study included 476 patients with T2DM with a mean age of 58 years [36; 79]. The patients were divided into groups by sex and age.
BMC Cardiovasc Disord
September 2025
Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, 6-1, Kishibe-Shinmachi, Suita, Osaka, 564-8565, Japan.
Background: Increased plasma levels of B-type natriuretic peptide (BNP) serve as a biomarker for heart failure (HF). This study aimed to develop a risk score to predict elevated BNP levels using traditional cardiovascular disease (CVD) risk factors.
Methods And Results: We analyzed data from 2809 Japanese individuals aged ≥ 40 years from the Suita Study, a population-based prospective cohort.