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Background: Obesity, which is caused by various congenital factors, lifestyle changes, and modernized eating habits, has recently emerged as a serious health concern in children and adolescents. According to the Korea National Health and Nutrition Examination Survey (KNHANES) conducted from 2007 to 2020, the prevalence of obesity and overweight in youth has shown an increasing trend over time. Notably, obesity has been studied in several studies. However, given its close association with rapidly changing societal environments and lifestyle patterns, continuous updates are necessary. Therefore, investigating the current state of obesity in children and adolescents is crucial. Herein, we investigated factors related to the prevalence of obesity.
Materials And Methods: We investigated 1912 adolescents between the ages of 12 and 18 years from 2017 to 2020 using data from the KNHANES. Known and suspected risk factors for lifestyle and eating habits were analyzed using univariate and multivariate logistic regression analyses.
Results: Our study revealed a gradual increase in the proportion of individuals having overweight and obesity. Regarding risk factors for obesity, in the unadjusted model, older age (Odds ratio [OR], 1.11), sedentary time ≥12 h (OR, 1.29), and a higher calorie intake from protein (OR, 1.06) were positively associated with obesity, whereas female sex (OR, 0.52) and sleep duration ≥8 h (OR, 0.56) were negatively associated with obesity. These trends remained consistent in the adjusted model, with older age (OR, 1.10), sedentary time ≥12 h (OR, 1.46), higher protein intake (OR, 1.05), and skipping dinner ≥3 times per week (OR, 2.22) being positively associated with obesity and female sex (OR, 0.60) and sleep duration of 6-8 h (OR, 0.54) and ≥8 h (OR, 0.48) being negatively associated with obesity.
Conclusion: Obesity in Korean adolescents was significantly correlated with shorter sleep duration, more sedentary time, higher protein intake, and frequent meal skipping at dinner. These results highlight the necessity of focused public health initiatives that support healthy living practices, including healthy eating habits, less sedentary activity, and more sleep time.
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http://dx.doi.org/10.3389/fnut.2025.1554218 | DOI Listing |
Pediatr Blood Cancer
September 2025
Acute Myeloid Leukemia Sub-Committee, Association of Childhood Leukemia Study (JACLS), Japan.
Background: Relapsed or refractory cases of pediatric acute myeloid leukemia (AML) have poor outcomes despite advancements in chemotherapy and hematopoietic stem cell transplantation (HSCT). While a second HSCT is often a salvage option, its outcomes vary widely, and prognostic factors remain unclear.
Objectives: This study aimed to evaluate outcomes and identify prognostic factors in pediatric patients with AML who underwent multiple HSCTs.
Alzheimers Dement
September 2025
School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Camperdown, Sydney, New South Wales, Australia.
Introduction: Risperidone is approved for behaviors and psychological symptoms of dementia (BPSD), despite modest efficacy and known risks. Identifying responsive symptoms, treatment modifiers, and predictors is crucial for personalized treatment.
Method: A one-stage individual participant data meta-analysis of six randomized controlled trials (risperidone: n = 1009; placebo: N = 712) was conducted.
Semin Dial
September 2025
Department of Nephrology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Background: In hyponatremic patients, concurrent dialysate flow during hemodialysis may be an ideal option to mitigate complications such as osmotic demyelination syndrome (ODS).
Methods: Present randomized controlled trial enrolled dialysis-requiring chronic kidney disease (CKD) and acute kidney injury (AKI) patients with serum sodium levels < 125 mEq/L during January 2020 over 16 months. Hemodynamically unstable patients, as well as those with a history of seizures and neurological conditions, were excluded.
J Assist Reprod Genet
September 2025
Morsani College of Medicine, Department of Obstetrics and Gynecology, University of South Florida, 2 Tampa General Circle, STC 6th Floor, Tampa, FL, 33606, USA.
Purpose: Prior studies in fresh embryo transfer IVF cycles have associated elevated serum progesterone level on day of ovulatory trigger, particularly if ≥ 1.5 ng/ml, with decreased pregnancy rates. A similar association has been found in intrauterine insemination (IUI) cycles using gonadotropins for ovulation induction.
View Article and Find Full Text PDFAnn Hematol
September 2025
Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland.
While frailty and anemia are prevalent conditions in aging linked to adverse outcomes, their relationship remains understudied in generally healthy older adults. We conducted a post-hoc observational study among all participants of DO-HEALTH, the largest European clinical trial designed to support healthy aging. Our analysis examined whether baseline hemoglobin levels and anemia are associated with being at least pre-frail at baseline and any yearly follow-up time point over three years.
View Article and Find Full Text PDF