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http://dx.doi.org/10.1111/apt.70186DOI Listing

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Advanced multidimensional quality evaluation of encapsulated peppermint oil products in various formulas.

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Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.

We investigated the actual label indications and quality of encapsulated peppermint oil (PO) products marketed as medicinal products for irritable bowel syndrome (IBS) or health food. Quality was multidimensionally evaluated with regard to the original plant source, content of PO and components of safety concern, and formulation. The original plant source was evaluated with reference to the criteria specified in the British and European pharmacopoeias and advanced GC-MS profiling tests, combined with simple discriminant analysis of the major 4 components (menthol, menthone, menthofuran, and isomenthone), which enabled evaluation of the various PO product formulations.

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