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http://dx.doi.org/10.1182/bloodadvances.2024015721 | DOI Listing |
Infect Drug Resist
September 2025
Department of Emergency Medicine, Affiliated Lu'an Hospital of Anhui Medical University, Lu'an, Anhui, 237005, People's Republic of China.
Hypervirulent is a recently identified pathotype characterized by high virulence and rapid dissemination. It is associated with invasive infections at multiple anatomical sites, including liver abscesses, necrotizing fasciitis, meningitis, myositis, and endophthalmitis. It has emerged as a significant threat to public health due to its aggressive clinical course and high mortality rate.
View Article and Find Full Text PDFInt Med Case Rep J
August 2025
Emergency and Trauma Care Research Center, Imam Reza General Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Arnold-Chiari Malformation Type I (ACM-I) is a congenital disorder that can lead to severe neurological symptoms. While decompression surgery is the standard treatment, postoperative complications such as cerebrospinal fluid (CSF) leakage and infections can result in critical outcomes. Here, we report a case of septic shock following decompression surgery in a patient with ACM-I, emphasizing the challenges in postoperative critical care management.
View Article and Find Full Text PDFNan Fang Yi Ke Da Xue Xue Bao
August 2025
Guangzhou Twelfth People's Hospital, Guangzhou 510700, China.
Objectives: To explore the efficacy of DSA-guided intrathecal drug delivery system combined with Acupoint Therapy for management of cancer pain and provide reference for its standardized clinical application. Methods and.
Results: Recommendations were formulated based on literature review and expert group discussion, and consensus was reached following expert consultation.
Cancer Epidemiol Biomarkers Prev
September 2025
Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, United States.
Background: Survivors of childhood acute lymphoblastic leukemia (ALL) frequently exhibit treatment-related neurocognitive impairment, although there is substantial interpatient variability in this outcome. Analysis of biomarkers that reflect the impact of chemotherapy during the two years of treatment for ALL offers the potential to identify children who have subclinical treatment-related neurotoxicity at a time when a protective intervention could prevent the development of persistent impairment.
Methods: We prospectively measured markers indicative of oxidative stress (8-hydroxydeoxyguanosine; 8OHdG) and neurodegeneration (total tau) in cerebrospinal fluid (CSF) collected at five timepoints before and during the first year of chemotherapy for ALL among 529 patients enrolled on DFCI ALL Consortium protocol 16-001 (NCT03020030).
Br J Anaesth
September 2025
Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, 200433, Shanghai, China. Electronic address: