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Aims: Conduct a systematic review and meta-analysis on the effects of motor intervention on social, communication, and cognitive skills in individuals (0-21 years) with autism spectrum disorder (ASD).
Methods: Seven databases were used to search for randomized control trials (RCT) implementing a motor intervention for children with ASD; and measured social, communication, and cognitive outcomes. Twenty-three RCTs were selected with 66 outcomes and 636 participants (range of mean age: 4.3 - 12.3 years).
Results: Motor interventions had a significant, positive effect on (1) all outcomes combined (i.e. social, communication, and cognitive) (: 0.41, = .01), (2) social (: 0.46, = .012) and (3) combined social/communication (: 0.47, = .01) domains, but not for the motor domain (SSMD: 0.45, = .25) or cognitive domain alone (SSMD: 0.22, = .18). In children above age nine, a 1-year increase in age corresponded to a 0.29 decrease in SSMD (less effective).
Conclusions: Motor interventions have a positive impact and should be considered when planning interventions for children with ASD.
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http://dx.doi.org/10.1080/01942638.2025.2498357 | DOI Listing |
Neurology
October 2025
Montreal Neurological Institute-Hospital, McGill University, Montreal, Canada.
Background And Objectives: Years before diagnosis of Parkinson disease (PD), dementia with Lewy bodies (DLB), or multiple system atrophy (MSA), mild prodromal manifestations can be detected. Longitudinal follow-up of people with prodromal synucleinopathy, particularly idiopathic/isolated REM sleep behavior disorder (iRBD), enables in-depth clinical phenotyping of early disease, which could facilitate stratification for clinical trials, provide the definition of appropriate end points, or predict phenoconversion more precisely. The aim of this study was to update and expand on previous studies assessing clinical evolution from iRBD to clinically diagnosed disease, up to 14 years before diagnosis.
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Université Grenoble Alpes, CNRS, Grenoble INP, TIMC, Grenoble, France.
Background And Objectives: We present a new Finite Element (FE) tongue model that was designed to precisely account for 3D tongue shapes produced during isolated French speech sounds by a male individual (RS). Such a high degree of realism will enable scientists to precisely and quantitatively assess, in a speaker-specific manner, hypotheses about speech motor control and the impact of tongue anatomy, muscle arrangements, and tongue dynamics in this context.
Methods: The shape and topology of the FE model were generated from 3D high resolution orofacial MR images of RS having his tongue in "neutral" posture.
PLoS One
September 2025
Graduate Institute of Injury Prevention and Control, College of Public Health, Taipei Medical University, Taipei City, Taiwan.
Background And Objectives: Fatality rates of motor vehicle crashes among the old population have risen, primarily in association with age-related declines in health and functional abilities. Comparatively little research has been conducted to examine the impacts of risk-taking behaviors (such as unhelmeted, unlicensed, and drunk riding) on fatalities among old motorcyclists.
Materials And Methods: This study employed the Taiwan National Traffic Crash Dataset from 2011 to 2022 to investigate fatal injuries among old motorcyclists.
PLoS Biol
September 2025
Center for Neural Science, Department of Biology and Department of Psychology, New York University, New York, New York, United States of America.
Investigating social and independent behavior structure in early life is critical for understanding development and brain maturation in social mammals. However, this investigation necessitates monitoring animals over weeks to months often with subsecond time resolution creating challenges for both lab studies focused on brief observation periods and field studies in which animal tracking can be imprecise. Here we used machine vision and two-week long continuous behavior recordings of families of gerbils, a highly social rodent, in large, undisturbed home environments to quantify the behavioral development of individual pups.
View Article and Find Full Text PDFPlast Reconstr Surg
September 2025
Department of Surgery, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
Background: Poor recovery of active glenohumeral external rotation (aGHER) after brachial plexus birth injury (BPBI) is common. Late spinal accessory nerve to infraspinatus motor branch (SAN-IS) transfer has been reported as effective. We investigated its efficacy in children over 4 years with BPBI.
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