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Background: Around 20%-50% of Chinese menopausal women experience insomnia, which is associated with elevated blood pressure (BP). Despite this, the population remains understudied. Qigong, a simple form of Chinese exercise, has been shown to improve insomnia and BP but has not been explicitly used to address menopausal symptoms in Chinese women. This study aims to test the feasibility of a Qigong-based intervention in enhancing sleep quality and BP control in this population.
Objective: This study aimed to develop and pilot test the feasibility of a culturally sensitive Qigong Used for Insomnia Therapy (QUIT) intervention in improving sleep quality and BP among Chinese menopausal women.
Methods: From August 2023 to May 2024, this study used a 1-group pretest-posttest design (N=22) to evaluate the QUIT intervention. The intervention consisted of a 10-minute Qigong demonstration video, a 10-minute practice and return demonstration and a 5-minute insomnia counseling session at baseline. Participants were instructed to engage in daily 10-minute Qigong practice for 1 month. Outcome measures, including sleep quality and BP, were assessed at baseline and at the 1-month follow-up. Data on demographics were collected via self-reported questionnaires. At the end of the study, participants were interviewed using semistructured questions to assess their perception of the intervention's feasibility. Qualitative data were analyzed using content analysis, with interviews transcribed and coded independently by the principal investigator and research assistant. Categories related to feasibility, adherence, and barriers were identified. Quantitative data were analyzed using SPSS 27.0 (IBM Corp), using descriptive statistics and paired sample t tests to assess changes in sleep quality and BP, with statistical significance set at .05.
Results: The mean age of participants was 53.78 (SD 8.79, range 42-74) years. Most participants lived with relatives or friends (20/22, 91%), were employed (16/22, 73%), were married (19/22, 86%), and had at least high school education (19/22, 86%). The mean 23-item Sleep Quality Scale score significantly improved from 18.59 (SD 11.41) at baseline to 15.64 (SD 9.65; mean difference 2.96, SD 7.04; t21=1.97, P=.03) after 1 month, indicating better sleep quality (the 23-item Sleep Quality Scale was reversely scored). There was a trend toward reduced systolic BP from 115.47 (SD 14.95) at baseline to 113.59 (SD 13.93; mean difference -0.89, SD 1.64; t21=-1.15, P=.26) after 1 month. Diastolic BP also improved from 74.69 (SD 10.81) at baseline to 71.41 (SD 16.82) at 1 month (mean difference -3.28, SD 4.04; t21=-0.81, P=.43).
Conclusions: The QUIT intervention was culturally sensitive, low-cost, and easy to implement. It showed significant improvements in sleep quality and trends toward reduced BP in Chinese menopausal women. Further investigation is recommended to further test the QUIT intervention to establish a robust program across different states. Once validated, the QUIT intervention may be implemented in various clinical settings to help Chinese menopausal women achieve optimal sleep quality and BP management.
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http://dx.doi.org/10.2196/70226 | DOI Listing |
JMIR Form Res
September 2025
Department of Psychological Science, School of Social Ecology, University of California, Irvine, 4201 Social and Behavioral Sciences Gateway, Irvine, CA, 92697, United States, 1 203-887-8857.
Background: Rates of loneliness have risen sharply since the onset of the COVID-19 pandemic, largely due to disruptions in social relationships and daily routines, with college students experiencing some of the greatest increases. While prevention programs targeting loneliness have been developed, their success has been limited. One promising approach may lie in enhancing the quality of existing relationships rather than simply increasing social interactions during periods of acute loneliness.
View Article and Find Full Text PDFJAMA Intern Med
September 2025
Bayer CC AG, Basel, Switzerland.
Importance: There is an unmet need for long-term, safe, effective, and hormone-free treatments for menopausal symptoms, including vasomotor symptoms (VMS) and sleep disturbances.
Objective: To evaluate the 52-week efficacy and safety of elinzanetant, a dual neurokinin-targeted therapy, for treating moderate to severe VMS associated with menopause.
Design, Setting, And Participants: OASIS-3 was a double-blind, placebo-controlled, randomized phase 3 clinical trial that was conducted at 83 sites in North America and Europe from August 27, 2021, to February 12, 2024, and included postmenopausal women aged 40 to 65 years who were seeking treatment for moderate to severe VMS (no requirement for a minimum number of VMS events per week).
JAMA Netw Open
September 2025
School of Rehabilitation Science, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Importance: The cost-effectiveness of adding early in-bed cycling to usual physiotherapy among adults receiving mechanical ventilation in the intensive care unit (ICU) compared with usual physiotherapy alone is unknown.
Objective: To evaluate the cost-effectiveness of in-bed cycling plus usual physiotherapy compared with usual therapy alone in the Critical Care Cycling to Improve Lower Extremity Strength (CYCLE) randomized clinical trial.
Design, Setting, And Participants: This trial-based economic evaluation with a 90-day time horizon compared early cycling plus usual physiotherapy vs usual physiotherapy alone from a societal perspective.
Crohns Colitis 360
July 2025
Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Introduction: Acute severe ulcerative colitis (ASUC) typically requires hospitalization for intravenous (IV) corticosteroid treatment and monitoring. In response to the need to reduce inpatient stays, especially during the COVID-19 pandemic, outpatient treatment models have gained interest. This study evaluated the feasibility, safety, and patient satisfaction of outpatient IV corticosteroid treatment for ASUC.
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