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The fracture volume is gradually changed with the depletion of fracture pressure during the production process. However, there are few flowback models available so far that can estimate the fracture volume loss using pressure transient and rate transient data. The initial flowback involves producing back the fracturing fluid after hydraulic fracturing, while the second flowback involves producing back the preloading fluid injected into the parent wells before fracturing of child wells. The main objective of this research is to compare the initial and second flowback data to capture the changes in fracture volume after production and preload processes. Such a comparison is useful for evaluating well performance and optimizing fracturing operations. We construct rate-normalized pressure (RNP) versus material balance time (MBT) diagnostic plots using both initial and second flowback data (FB and FB, respectively) of six multi-fractured horizontal wells completed in Niobrara and Codell formations in DJ Basin. In general, the slope of RNP plot during the FB period is higher than that during the FB period, indicating a potential loss of fracture volume from the FB to the FB period. We estimate the changes in effective fracture volume ( ) by analyzing the changes in the RNP slope and total compressibility between these two flowback periods. during FB is in general 3%-45% lower than that during FB. We also compare the drive mechanisms for the two flowback periods by calculating the compaction-drive index (CDI), hydrocarbon-drive index (HDI), and water-drive index (WDI). The dominant drive mechanism during both flowback periods is CDI, but its contribution is reduced by 16% in the FB period. This drop is generally compensated by a relatively higher HDI during this period. The loss of effective fracture volume might be attributed to the pressure depletion in fractures, which occurs during the production period and can extend 800 days.
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http://dx.doi.org/10.1007/s40789-025-00754-9 | DOI Listing |
Front Bioeng Biotechnol
August 2025
Department of Orthopaedics and Traumatology, Medical University of Innsbruck, Innsbruck, Austria.
Bone infections caused by and are serious complications in orthopedic surgery. These infections commonly occur in joint replacements, fracture management, and bone grafting procedures. Rapid and accurate pathogen-specific diagnostic methods are urgently needed to support early clinical decisions.
View Article and Find Full Text PDFTissue Cell
September 2025
Department of Health and Sports Science, Toyo University School of Health and Sports Science, 1-7-11 Akabanedai, Kita-ku, Tokyo 115-8650, Japan. Electronic address:
The development of new adjunct therapies to support bone healing remains an important clinical challenge. Eggshell membrane (ESM), a natural biomaterial derived from chicken eggs, has recently attracted attention for its safety, biocompatibility, and cost-effectiveness. We aimed to evaluate the effects of ESM supplementation on bone healing in a rat tibial drill-hole injury model.
View Article and Find Full Text PDFJ Craniofac Surg
September 2025
Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan.
Resorbable implants are increasingly used in orbital wall fracture reconstruction because of their ability to provide temporary structural support without the long-term complications associated with permanent materials. However, the long-term effects of implant resorption on orbital morphology are unclear. This retrospective study evaluated volumetric changes over time following reconstruction using 2 types of resorbable plates: uncalcined hydroxyapatite/poly-L-lactic acid (u-HA/PLLA) and poly-L-lactic acid/polyglycolic acid (PLLA/PGA).
View Article and Find Full Text PDFUltrasound Med Biol
September 2025
School of Electronic Science and Engineering, Nanjing University, Nanjing, Jiangsu, China. Electronic address:
Objective: Three-dimensional (3D) ultrasound imaging overcomes the limitations of 2D ultrasound images by providing comprehensive spatial information. However, challenges remain when imaging larger body parts like legs and arms using traditional linear transducer arrays. The main difficulties include limited scanning range and angle, bone interference that affects penetration depth, and registration difficulties caused by squeezing targets.
View Article and Find Full Text PDFInt Endod J
September 2025
Department of Endodontics, Fluminense Federal University, Rio de Janeiro, Brazil.
Aim: To evaluate dentine loss in mesial canals of mandibular molars following instrument fragment retrieval using two techniques.
Methodology: Ten mesial roots of mandibular molars with Type II configuration were selected and scanned in a micro-computed tomography (CT) device. After canal preparation, a 3-mm fragment of a size 35/0.