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This review explores the transformative potential of artificial intelligence (AI) in the diagnosis and management of biliopancreatic disorders. By leveraging cutting-edge techniques, such as deep learning and convolutional neural networks, AI has significantly advanced gastroenterology, particularly in endoscopic procedures, such as colonoscopy; upper endoscopy; and capsule endoscopy. These applications enhance adenoma detection rates and improve lesion characterization and diagnostic accuracy. AI's integration in cross-sectional imaging modalities, such as computed tomography and magnetic resonance imaging, has remarkable potential. Models have demonstrated high accuracy in identifying pancreatic ductal adenocarcinoma; pancreatic cystic lesions; and pancreatic neuroendocrine tumors, aiding in early diagnosis; resectability assessment; and personalized treatment planning. In advanced endoscopic procedures, such as digital single-operator cholangioscopy and endoscopic ultrasound, AI enhances anatomic recognition and improves lesion classification, with a potential for reduction in procedural variability, enabling more consistent diagnostic and therapeutic outcomes. Promising applications in biliopancreatic endoscopy include the detection of biliary stenosis, classification of dysplastic precursor lesions, and assessment of pancreatic abnormalities. This review aims to capture the current state of AI application in biliopancreatic disorders, summarizing the results of early studies and paving the path for future directions.
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http://dx.doi.org/10.1053/j.gastro.2025.04.011 | DOI Listing |
Obes Surg
September 2025
Obstetrical Department, Affiliated Maternity and Child Health Care Hospital of Nantong University, nantong, China.
The increasing number of women of reproductive age undergoing bariatric surgery has brought more attention to pregnancies following these procedures. However, the impact of different types of bariatric surgery on pregnancy outcomes remains unclear. This study aims to systematically investigate the effects of four types of bariatric surgery-Roux-en-Y gastric bypass (RYGB), laparoscopic adjustable gastric banding (LAGB), sleeve gastrectomy (SG), and biliopancreatic diversion (BPD)-on pregnancy outcomes.
View Article and Find Full Text PDFCurr Issues Mol Biol
August 2025
Endocrine Unit, UNESCO Chair on Adolescent Health Care, University Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Type 2 diabetes mellitus (T2DM) is a multifactorial disorder defined by insulin resistance, β-cell dysfunction, and chronic hyperglycemia. Although peripheral mechanisms have been extensively studied, increasing evidence implicates the gastrointestinal tract in disease onset. Insights from bariatric surgery, gut hormone signaling, and incretin-based therapies suggest that the gut contributes actively beyond nutrient absorption.
View Article and Find Full Text PDFWorld J Gastrointest Endosc
August 2025
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kasr Al-Aini School of Medicine, Cairo University, Cairo 11562, Egypt.
Endoscopic ultrasound (EUS) is an indispensable tool for the diagnosis and management of various diseases, particularly biliopancreatic disorders, as it provides detailed visualization of the gastrointestinal tract and surrounding structures. As the demand for diagnostic and interventional EUS procedures increases, ensuring high-quality training for endoscopists is essential to improve patient outcomes. This mini-review provides an overview of the current state of EUS training and emphasizes the importance of a structured approach that integrates theoretical knowledge and hands-on experience.
View Article and Find Full Text PDFClin Nutr
September 2025
Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Austria.
Background: Metabolic bariatric surgery (MBS) has been shown to provide significant improvements in metabolic dysfunction-associated steatotic liver disease (MASLD) but its effects on liver fibrosis remain controversial.
Aims: To establish a rodent model of liver fibrosis progression after MBS and to investigate the impact of post-operative diets and different bypass lengths on liver fibrosis progression, weight dynamics, and metabolic effects.
Methods: Male Sprague Dawley rats were subjected to either sham surgery or one anastomosis gastric bypass (OAGB) with moderate or extended biliopancreatic limb lengths, followed by dietary manipulation with a high-fat, high-fructose and high-cholesterol diet (FFC) or standard chow.
Objective: To determine the prevalence and clinical characteristics of post-endoscopic retrograde cholangiopancreatography (ERCP) complications, particularly acute pancreatitis, in patients with biliopancreatic disorders treated at a secondary-level referral hospital in Mexico between April 1, 2020, and December 31, 2023, and to compare outcomes between patients who received biliary stents and those who did not.
Materials And Methods: This was an observational and retrospective study conducted at a secondary-level hospital in Mexico. A total of 151 medical records of patients who underwent ERCP were reviewed.