Publications by authors named "Magdalena Mairinger"
Background: Metabolic bariatric surgery (MBS) has been shown to provide significant improvements in metabolic dysfunction-associated steatotic liver disease (MASLD) but its effects on liver fibrosis remain controversial.
Aims: To establish a rodent model of liver fibrosis progression after MBS and to investigate the impact of post-operative diets and different bypass lengths on liver fibrosis progression, weight dynamics, and metabolic effects.
Methods: Male Sprague Dawley rats were subjected to either sham surgery or one anastomosis gastric bypass (OAGB) with moderate or extended biliopancreatic limb lengths, followed by dietary manipulation with a high-fat, high-fructose and high-cholesterol diet (FFC) or standard chow.
Article Synopsis
- Metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis (MASH) are prevalent in obese individuals and may improve with metabolic/bariatric surgery (MBS).
- A study of 93 patients showed significant reductions in liver stiffness and indicators of liver health three months after MBS, correlating with weight loss.
- Improvements in liver conditions were evident as early as three months post-surgery, indicated by lower liver stiffness measurements and liver injury markers.
Article Synopsis
- * Pouch resizing using a MiniMIZER® Gastric Ring can help manage weight regain caused by pouch dilatation and requires thorough pre-surgical evaluations, including endoscopies and imaging studies.
- * The article outlines the standardized procedures for pouch resizing, discusses indications for revisional surgery, pre-surgical assessments, and describes the surgical process and post-operative care necessary for successful outcomes.
Laparoscopic Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy (SADI-S) is a bariatric/metabolic procedure that has been gaining popularity in recent years. SADI-S strongly affects the secretion of various gut hormones, adipocytokines and incretins. From a mechanistic point of view, the operation combines malabsorption and restriction, and has been shown to have a long-lasting and significant impact on weight loss and remission of comorbidities.
View Article and Find Full Text PDFSurgical Technique of Diverted One-Anastomosis Gastric Bypass.
Surg Technol Int
October 2021
Laparoscopic diverted one-anastomosis gastric bypass (D-OAGB) is a bariatric procedure combining the principles of restriction, malabsorption, and other factors to induce weight loss. It is achieved by creating a narrow, long gastric pouch and bypassing a part of the small bowel (biliopancreatic limb). D-OAGB was first described by Dr.
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