98%
921
2 minutes
20
Transcatheter mitral leaflet repair is a non-surgical technique used to treat severe mitral regurgitation. The technique has matured significantly since its commercial introduction, and with device iteration and increasing operator experience, it is now an important treatment option for patients at higher risk for conventional mitral valve surgery. Randomised clinical trials have established the safety and efficacy of the technique in the treatment of primary and secondary mitral regurgitation, and its use was approved by the National Institute for Health and Care Excellence in 2019. This position statement summarises the clinical evidence and indications for the procedure and provides expert consensus on best practice in terms of patient selection, the procedure and post-procedure care. Standards are also described with respect to team composition, minimum case volume and collection of procedural and outcome data.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042289 | PMC |
http://dx.doi.org/10.15420/icr.2025.01 | DOI Listing |
Int J Oral Implantol (Berl)
September 2025
Purpose: To compare the accuracy of static guided surgery using a pilot drill guide and dynamic guided surgery for dental implant placement.
Materials And Methods: Partially edentulous adult patients requiring implant placement were randomly assigned to either the static guided surgery group using a pilot drill guide or the dynamic guided surgery group. Digital implant planning was conducted using intraoral scans and CBCT with planning software to determine the optimal prosthetic position.
Int J Oral Implantol (Berl)
September 2025
Purpose: To present a novel digital workflow (the Columbus Digital Bridge Protocol) for immediately loaded full-arch rehabilitations, integrating digital technologies throughout diagnostic, surgical and prosthetic phases, with a focus on the application of intraoral photogrammetry scanning.
Materials And Methods: The workflow presented in this article, successfully implemented in 14 patients, includes standardised clinical steps: digital diagnostic planning through matching of facial scans and CBCT data, surgical placement of four implants following tooth extraction, immediate post-surgical intraoral photogrammetry scanning using a three-step procedure (i.e.
Int J Oral Implantol (Berl)
September 2025
Background: Certain 3D interrelationships between adjacent implants can potentially predispose to prosthetic and biological complications.
Materials And Methods: Patient records with adjacent dental implants were assessed to evaluate the effects of vertical, horizontal and angulation interrelationships between splinted compared to non-splinted implant restorations on the occurrence of biological and prosthetic complications. Data on patient- and implant-related variables were collected at baseline (T1) during prosthesis placement and at the last follow-up appointment (T2).
Climacteric
September 2025
Escuela de Postgrado en Salud, Universidad Espíritu Santo, Samborondón, Ecuador.
Objective: Androgens have been prescribed to alleviate symptoms in midlife women, but evidence regarding benefits and risks remains limited, with no clearly established indications for Testosterone therapy. In many Latin American countries, Testosterone is prescribed without specific guidelines, making it difficult to identify patients who might benefit. This position statement aims to summarize evidence and provide a Latin American perspective on androgen therapy in midlife and older women.
View Article and Find Full Text PDFCurr Opin Pulm Med
September 2025
Departments of Medicine and Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA.
Purpose Of Review: The advent of CFTR modulators and the adoption of telemedicine during the COVID-19 pandemic have prompted reconsideration of cystic fibrosis (CF) care models. This review explores how care delivery may evolve in response to these changes.
Recent Findings: Emerging evidence highlights the heterogeneity in response to CFTR modulators, with some patients continuing to experience disease progression.