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Background And Aims: With surges in digital technologies, concerns over adolescents' screen use have intensified. Previous studies often relied on self-reported screen time, neglecting the experiential and motivational aspects of different screen activities (e.g. social media, gaming, and smartphones), possibly leading to heterogeneous associations. This study aimed to examine whether the severity of problematic screen use, conceptualized as a continuous measure of screen-related functional impairment, plays a more central role in development than self-reported screen time or phone-checking frequency, and to explore its influence within the broader adolescent ecosystem (i.e. family conflict, peer involvement, and school participation).
Methods: Cohort data were obtained from the Adolescent Brain Cognitive Development (ABCD) study Release 5.1. Screen use was obtained from self-report questionnaires, capturing both activity time and functional impairments. Among cross-sectional networks derived from 9,054 youth (4,272 girls, 47.18%) at 2-year follow-up (T2, ages 11-12 years) and 4,007 youth (1,896 girls, 47.32%) at 4-year follow-up (T4, ages 13-14 years), problematic use showed higher centrality than screen time and checking behavior, owing to stronger connections with behavioral tendencies. Cross-lagged-panel-network analyses of problematic use included 3,954 youth (1,863 girls, 47.12%).
Results: Problematic use exhibited high out-strength, which was associated with worsening psychopathologies and environmental conditions. Conversely, problematic use at T4 appeared less influenced by factors at T2.
Conclusion: This study underscores the pivotal role of problematic screen use, which showed greater centrality and stronger predictive effects on adolescent well-being than self-reported screen time, highlighting the need for policies and interventions addressing screen-related functional impairments to promote healthier screen habits in developing youth.
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http://dx.doi.org/10.1556/2006.2025.00035 | DOI Listing |
J Am Coll Health
September 2025
Department of Psychiatry, University of Oxford, Oxford, UK.
Objective: Many students who need mental health support do not receive it. We examined associations between perceived barriers and university mental health service access. Participants: First-year Oxford University undergraduates ( = 443) with unmet mental health needs.
View Article and Find Full Text PDFCien Saude Colet
August 2025
Departamento de Medicina Social, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo. Ribeirão Preto SP Brasil.
The present study aimed to investigate the relationship between screen time and the frequency of consumption of ultra-processed foods (UPF) in overweight pregnant women. This was a cross-sectional study that used baseline data from a randomized clinical trial conducted in the Primary Health Care (PHC) network of a Brazilian municipality between 2018 and 2021. Data from the Food Consumption Markers form were used.
View Article and Find Full Text PDFCien Saude Colet
August 2025
Faculdade de Medicina, Universidade Federal do Rio Grande Faculdade de Medicina. R. General Osório s/n, Centro. 96200-400 Rio Grande RS Brasil.
Screen time has prompted investigations by researchers worldwide because of its impact on general health. This research aimed to analyze excessive screen time from a Brazilian national survey among adults and older people and to verify the immediate effect of the COVID-19 pandemic on the evolution of the behavior. A panel study using the survey database between 2016-2022, in a sample of 254,600 Brazilian adults and elderly residents in capital cities.
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Systems Biology and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America.
Gene signatures predictive of chemotherapeutic response have the potential to extend the reach of precision medicine by allowing oncologists to optimize treatment for individuals. Most published predictive signatures are only capable of predicting response for individual drugs, but most chemotherapy regimens utilize combinations of different agents. We propose a unified framework, called the chemogram, that uses predictive signatures to rank the relative predicted sensitivity of different drugs for individual tumors.
View Article and Find Full Text PDFJ Laparoendosc Adv Surg Tech A
September 2025
Department of Anesthesiology, Shandong Provincial Third Hospital, Shandong University, Jinan, China.
This study aimed to identify the biomarkers that was associated with the postoperative incisional pain in patients with acute cholecystitis undergoing laparoscopic cholecystectomy surgery (ACC-LC). Sixty ACC-LC patients were enrolled and divided into mild pain (MP) and moderate-to-severe pain (MSP) groups based on their visual analog scale (VAS) scores 24 hours postoperatively. RNA sequencing was used to screen the potential pain associated markers, and ELISA were used to analyze the expression of one identified marker, CXCR5 in peripheral blood mononuclear cells (PBMCs).
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