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We investigated the association of chrononutrition, sleep behavior, and chronotype with adiposity and appetite sensations among 220 Malaysian adults (M/F = 57/163; aged 22.02 ± 5.19). Meal times, dietary intake, and appetite sensations (before and after meals) were recorded for two weekdays and one weekend. Sleep behavior was tracked objectively via activity wristband, chronotype was assessed by the Morningness-Eveningness Questionnaire, and anthropometrics/body compositions were measured. Overall participants had significantly later breakfast, lunch, eating midpoint, wake up time, sleep duration, compared to weekdays. Those who belonged to the delay eating jetlag group had significantly higher weekday, but lower weekend eating windows. Larger caloric intake later in the day was significantly associated with lower body mass and adiposity. Delay lunch jetlag class was significantly associated with higher waist-hip ratio. Delayed morning and afternoon chrononutrition behaviors were associated with higher hunger and eating thoughts, and lower fullness sensations pre- and post-meals. Morningness was associated with lower satisfaction and fullness sensations post-breakfast, but higher same sensations pre-dinner. In conclusion, larger caloric intake later in the day and advanced lunch jetlag led to lower adiposity, while delayed chrononutrition behaviours were associated with higher pre- and post-meal appetite sensations.
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http://dx.doi.org/10.1080/07420528.2025.2495161 | DOI Listing |
Clin Nutr ESPEN
September 2025
Laboratório de Nutrição e Metabolismo (LANUM), Faculdade de Nutrição, Universidade Federal de Alagoas, Campus AC Simões - Av. Lourival Melo Mota, s/n, Cidade Universitária - Maceió, AL, 57072-900, Brazil. Electronic address:
Background: Obesity and the consumption of ultra-processed foods (UPF) are associated with gut microbiota composition and diversity, which may contribute to alterations in the regulation of hormones involved in satiety, given the gut microbiota's role in regulating host appetite. Therefore, this study aimed to investigate the association of gut microbiota composition and alpha-diversity at the genus-level on postprandial changes in satiety hormones, and appetitive measures in individuals with obesity, given either a meal rich in UPF or a meal without UPF.
Methods: Individuals were randomized to two groups: a) a non-UPF meal and b) a UPF meal.
Nat Commun
August 2025
Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
Olfactory perception of food odors is a key determinant of eating behavior, including triggering appetite, facilitating food seeking and influencing food choice. While transient food-related olfactory cues stimulate appetite and provoke cravings in states of hunger, emerging evidence implies that prolonged and sustained exposure to food-derived odor (FO) suppresses feeding. However, the mechanisms by which olfaction induces hypophagia remain elusive.
View Article and Find Full Text PDFElife
August 2025
Department of Biological Sciences, Ohio University, Athens, United States.
The intricate relationship between the dopaminergic system and olfactory associative learning in has been an intense scientific inquiry. Leveraging the formidable genetic tools, we conducted a screening of 57 dopaminergic drivers, leading to the discovery of DAN-c1 driver, uniquely targeting a pair of dopaminergic neurons (DANs) in the larval brain. While the involvement of excitatory D1-like receptors is well established, the role of D2-like receptors (D2Rs) remains underexplored.
View Article and Find Full Text PDFAppetite
August 2025
Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany; German Centre for Mental Health (DZPG), Bochum, Germany; Bielefeld University, University Hospital OWL, Protestant Hospital of Bethel Foundation, University Clinic of Psy
Interoception, the perception of body signals, which is crucial for maintaining metabolic homeostasis, is asserted to play a vital role in obesity. Despite conceptual assumptions that insular interoceptive functioning contributes to obesity risk, predominantly through modulating motor cortices, this link has not been extensively explored. Therefore, to further investigate neural and psychological components underlying the processing of food cues with a specific focus on insula-based interoceptive processing, this study assessed blood oxygenation level-dependent (BOLD) responses via functional magnetic resonance tomography (fMRI) in 45 healthy participants (31 females/14 males, age 35.
View Article and Find Full Text PDFCancer Control
July 2025
Department of Internal Medical, Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey.
IntroductionCisplatin is particularly recognized for its adverse effects, most notably its impact on chemosensory perception.MethodsThis cross-sectional study enrolled 98 cancer patients undergoing cisplatin therapy from April 2022 to December 2023. Patients were administered the Chemotherapy-Induced Taste Alteration Scale (CITAS) and the Rhodes Index of Nausea, Vomiting, and Retching (RINVR).
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