98%
921
2 minutes
20
The present study attempts to clarify the relationship between psychopathy, the therapeutic alliance, and success of offender treatment. In a German sample of = 89 convicted men in addiction treatment, we examined whether early therapeutic alliance ratings moderated the relationship between psychopathy, as measured by the Psychopathy Checklist - Revised (PCL-R), and treatment success within the first 6 months. Results indicated that a moderation model is appropriate, as the association between total PCL-R and treatment success differed as a function of perceived therapeutic alliance. Specifically, high psychopathy impaired treatment success when the alliance was simultaneously poor. Conversely, a good alliance seemed to buffer the adverse effects of psychopathy. No differential associations were found for PCL-R Factor 1 and Factor 2, and the moderation model held for both client-rated as well as therapist-rated alliance. Implications for improving treatment programs for psychopathic patients are discussed.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/0306624X251337484 | DOI Listing |
J Med Internet Res
September 2025
Department of Psychiatry, Helsinki University Hospital and Helsinki University, Helsinki, Finland.
Background: Internet-based cognitive behavioral therapies (iCBTs) are typically categorized into 2 types: therapist-assisted and self-guided. Both formats have accumulated substantial evidence supporting their cost-effectiveness and efficacy in treating a range of mental health conditions. However, therapist-assisted iCBTs tend to show lower dropout rates than self-guided versions.
View Article and Find Full Text PDFAdv Mater
September 2025
Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico, Universitat de València-Universitat Politècnica de València, Camino de Vera s/n, Valencia, 46022, Spain.
Bioorthogonal chemistry that can be controlled through near-infrared (NIR) light is a promising route to therapeutics. This study proposes a method to intracellularly photoactivate prodrugs using plasmonic gold nanostars (AuNSt) and NIR irradiation. Two strategies are followed.
View Article and Find Full Text PDFArch Osteoporos
September 2025
School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Unlabelled: The National Osteoporosis Guideline Group (NOGG) has updated the revised UK guideline for the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older. This guideline is relevant for all healthcare professionals involved in osteoporosis management.
Introduction: The UK National Osteoporosis Guideline Group (NOGG) first produced a guideline on the prevention and treatment of osteoporosis in 2008, with updates in 2013, 2017 and 2021.
Lupus Sci Med
September 2025
Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Background: SLE has increased risk of invasive pneumococcal disease due to immune dysregulation and immunosuppression. European Alliance of Associations for Rheumatology recommendations suggest sequential vaccination with conjugate vaccine, followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23). However, data on immunogenicity of sequential vaccination in SLE are limited.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Postgraduate training base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, China.
Asthma is a chronic inflammatory respiratory disease influenced by genetic and environmental factors. Emerging evidence suggests that microplastics and nanoplastics (NPs) pose significant health risks. When inhaled, these tiny particles can accumulate in the lungs, triggering inflammation, oxidative stress, and other disruptions in pulmonary function.
View Article and Find Full Text PDF